New Delhi, June 22 (IANS) Eleven individuals who received the AstraZeneca-Oxford Covid-19 vaccine have developed a rare neurological disorder called Guillain-Barre syndrome, clinicians in India and England have reported in two separate studies.The studies, published in the peer-reviewed medical journal Annals of Neurology, describe an unusual variant of Guillain-Barre syndrome characterised by prominent facial weakness. All the eleven cases were among people who had received that vaccine 10-22 days earlier.Seven cases were reported from a regional medical center in Kerala, India, where approximately 1.2 million people were vaccinated with the AstraZeneca Covid-19 vaccine till April 22. The cases occurred within two weeks of the first dose of vaccination."Six out of the seven patients progressed to areflexic quadriplegia and required mechanical ventilatory support," said Boby Varkey Maramattom, from the Department of Neurology, Aster Medcity, Kochi, Kerala."The frequency of GBS was 1.4 to 10 fold higher than that expected in this period for a population of this magnitude. In addition, the frequency of bilateral facial weakness, which typically occurs in less than 20 per cent of GBS cases, suggests a pattern associated with the vaccination," he added.Four cases were reported from Nottingham, England, in which approximately 700,000 people received the same vaccine. These were characterised by bifacial weakness with a paraesthesias variant of GBS occurring within three weeks of vaccination with the Oxford-AstraZeneca SARS-CoV-2 vaccine."This rare neurological syndrome has previously been reported in association with SARS-CoV-2 infection itself. Our cases were given either intravenous immunoglobulin, oral steroids, or no treatment," said Jonathan Rhys Evans, Department of Neurology, Nottingham University Hospitals NHS Trust, UK."If the link is causal it could be due to a cross-reactive immune response to the SARS-CoV-2 spike protein and components of the peripheral immune system," wrote the authors of the report from England.While the benefits of vaccination substantially outweigh the risk of this relatively rare outcome (5.8 per million), the research groups stressed that clinicians should be alert to this possible adverse event and look for this rare neurological syndrome following administration of Covid-19 vaccines."We suggest vigilance for cases of bifacial weakness with paraesthesias variant GBS following vaccination for SARS-CoV-2 and that post-vaccination surveillance programmes ensure robust data capture of this outcome, to assess for causality," Evans said.--IANSrvt/dpb
New York, June 19 (IANS) Older adults who struggle to fall asleep and experience frequent night awakenings are at high risk for developing dementia or dying early from any cause, a new study suggests.The findings, published in the Journal of Sleep Research, indicated that people who reported routinely experiencing difficulty falling asleep had a 49 per cent increased risk of dementia.And those who often woke in the night and had difficulty falling back asleep had a 39 per cent increased risk of dementia, reports CNN."We found a strong association between frequent difficulty falling asleep and nighttime awakenings and dementia and early death from any cause, even after we controlled for things like depression, sex, income, education and chronic conditions," said researcher Rebecca Robbins from Harvard Medical School.For the study, the team analysed data collected by the National Health and Aging Trends Study (NHATS), which conducts annual in-person interviews with a nationally representative sample of 6,376 Medicare beneficiaries.Data from between 2011 and 2018 were examined for the new study, with a focus on people in the highest risk category -- those who said they had sleep issues "most nights or almost every night".Self-reported sleep difficulties by participants in the study were then compared to each participant's medical records.The study found that people who had trouble falling asleep most nights had about a 44 per cent increased risk of early death from any cause.Those who said they often woke in the night and struggled to return to sleep had a somewhat higher risk -- a 56 per cent increased risk of early death from any cause."These results contribute to existing knowledge that sleep plays a very important role, every night, for reducing our long term risk for neural cognitive decline and all-cause mortality," said Robbins.--IANSvc/sdr/
Lifestyle disorders are a major cause of death in almost every country now. The occurrence of these problems is not a one-day process; people suffer due to long-time ignorance of their health care. Some of the lifestyle disorders are obesity, diabetes, cardiovascular diseases, cancers, strokes, Chronic Obstructive Pulmonary Disease (COPD), arthritis, and mental health issues.
Himanshu Rai, Chief Dietician and Nutritionist at Think You shares some of the leading causes of lifestyle disorders:
If your eating habits are linked to skipping meals, overeating, oily-fried-sugary meals, then you could be in the trap of lifestyle disorders. As per the WHO, "A healthy diet helps to protect against poor nutrition in all its forms and lifestyle-related health issues such as diabetes, heart diseases, strokes, cancers and brain disorders also." Eating healthy meals, not skipping meals and food that contains ingredients from all the major food groups (cereals, legumes and pulses, milk and meat, fruits and vegetables, fat and sugar) would be helpful to protect you from lifestyle disorders.
Also, Read► Covid-19 Changed Indians' Outlook on Dietary and Lifestyle
Lack Of Physical Activity
Lack of physical activity may lead to obesity or being overweight and it may lead to several other disorders such as cardiovascular diseases, diabetes, cancers and various others. The WHO suggests regular physical activity is very helpful for the prevention of diseases and improves the overall quality of life. As per WHO, adults should do 150 - 300 minutes of moderate-to-intense physical activity every week to provide significant benefits to overall health.
Lack Of Sleep
According to CDC (Centers for Disease Control and Prevention), poor sleep has been linked to diabetes, cardiovascular diseases, depression and obesity. In the case of diabetes, it has been linked to poor control of blood sugar levels. Whereas, in cardiovascular diseases, persons with poor sleeping are found to be at increased risk of high blood pressure, stroke, coronary heart diseases and irregular heartbeats. In obesity, short sleep duration results in metabolic changes, which are linked to obesity. Sleep disturbances for a long time have been one of the important symptoms of depression also.
As per Mayo Clinic, long-term stress puts the body on over-exposure to cortisol hormone and other stress hormones, which affects your body's normal health process. Overexposure to stress results in heart diseases, weight gain, depression, anxiety, digestive problems, sleep issues, headaches and memory issues. Stress management is very important to keep away from the different health issues.
Also, Read► To Keep Your Immune System In Its Prime
Smoking affects almost all the organs in a bad manner. Direct smoking may lead to different serious health concerns such as cancer, heart diseases, diabetes, stroke, lung disease, COPD (Chronic Obstructive Pulmonary Disease), etc. Whereas second-hand smoke causes stroke, coronary heart diseases, lung cancer, etc in adults. In children, second-hand smoke causes sudden infant death syndrome, acute respiratory infections, middle ear disease, more severe asthma, respiratory symptoms, and slowed lung growth.
Excess Alcohol Consumption
Excess alcohol drinking in the long term may lead to chronic diseases such as heart diseases, stroke, liver diseases, cancer, mental issues, digestive issues and several others. Whereas in short term, it causes accidents, violence, alcohol poisoning, risky sexual behaviours, miscarriage and stillbirth in pregnant women.
Mahatma Gandhi once wrote, "Instead of using the body as a temple of God we use it as a vehicle for indulgences, and are not ashamed to run to medical men for help in our effort to increase them and abuse the earthly tabernacle."
This statement is well connected to today's lifestyle disorders also; it means we are neglecting the power of prevention, doing excess and inviting lifestyle disorders.
Lifestyle disorders can be easily prevented with the help of eating nutritious meals on time, proper physical activity, proper sleep, stress management and avoiding alcohol and smoke.
Read More► 5 Healthy Ingredients to Help Channel Your Inner Boss Lady
Lucknow, May 26 (IANS) The King George's Medical University (KGMU) has achieved another feat by helping a 35-year-old Covid-19 positive woman with a rare immune system disorder deliver a healthy baby girl.The baby was delivered through C-section surgery at KGMU.The doctors said both, the woman and the baby, are fine and have been discharged.The woman, Deepika Tiwari, was suffering from 'Idiopathic Thrombocytopenic Purpura' (ITP) in which the patient's immune system destroys platelets, resulting in internal bleeding or from the skin.However, the management and treatment of KGMU doctors helped the patient in safe delivery."Tears rolled out when I was told that my wife had delivered a healthy girl and both were stable," said Shailendra Tiwari, the woman's husband.Doctors said ITP can affect both children and adults.Children often develop ITP after a viral infection and usually recover fully without treatment. In adults, ITP is often long-term or chronic. It affects three persons in a population of 1 lakh.Dean, medical and head of obstetrics and gynaecology department, Prof Uma Singh said, "Deepika Tiwari, with 38-week-and-six-day pregnancy, came to Queen Mary Hospital with complaint of abdominal pain on May 15 where she was found Covid positive. As per the protocol, she was shifted to Covid hospital at the RALC building. Tests showed her platelet counts were 18,000 cells/microliter and also confirmed her as a patient of ITP."Since platelets help the blood clot, when their number decreases the risk of bleeding increases. If they fall below 10,000 platelets per microliter it might become difficult to stop internal bleeding even without any injury.Therefore, the KGMU gynaecology team transfused four units of platelets. Besides, Intravenous immunoglobulin 80 GM worth approximately Rs 3 lakh was given free of cost to the patient, said Dr Uma Singh.KGMU vice-chancellor Lt-Gen Bipin Puri has congratulated the team members of the gynaecology department for the feat.--IANSamita/in
New Delhi, May 21 (IANS) The Coronavirus pandemic which started last year has taken a heavy toll on the working mothers in India with significant reduction in their average sleep time and more than two-fold jump in time taken to care for elderly in the family, a nationwide survey showed on Friday.
Working mothers in the country are now sleeping for only 5.50 hours per day as compared to 6.50 hours every day on average in pre-Covid era (before 2020), a reduction of about 17 per cent.
They are now spending 01.50 hours more taking care of the elderly/others in the family than in pre-Covid times, according to a survey carried out by market research agency Market Xcel Data Matrix covering 1,200 working mothers across the country.
The pandemic has also altered working mothers' routine and lifestyle -- their time of exercise and entertainment has also been reduced significantly.
Juggling between various responsibilities, they are struggling hard to finish their office work and are spending 08.55 hours to finish office work as compared to 06.50 hours earlier. Their household work has also gone up with the absence of housemaids in many cases.
Moreover, the working mothers are spending more time on their children's education now, with the absence of proper guidance in schools. Around 30 per cent women reported more household chores since the pandemic started and about 26 per cent said there were more childcare responsibilities.
As many as 30 per cent women also reported mental health issues since 2020 while another 26 per cent said they were having some kind of physical health issues.
"The present pandemic situation has had a ripple effect on everybody's life. The working mothers have especially been impacted who are burdened and stressed working round the clock fulfilling professional responsibilities and household duties," said Ashwani Arora, Senior Vice President, Market Xcel Data Matrix, in a statement on the Friday.
"Multitasking and playing many roles simultaneously is gradually becoming hectic. Working mothers have to compromise with their exercise and sleep. Managing office and home school (of kids) at the same time at the same pace is definitely not easy and we need to give some extra care for the caregivers," Arora added.
For the survey, 1,200 working mothers, aged between 25-45 were surveyed in 17 states across the country.
Washington, May 13 (IANS) The US Centers for Disease Control and Prevention have confirmed 28 cases, including six in men, of a rare blood clotting disorder in adults who have received the Johnson & Johnson Covid-19 vaccine, the media reported on Thursday.The number of cases has increased from 15 last month, all of which were in women, the New York Times reported. Although the latest report has identified a handful of cases in men, women -- especially those between the ages of 30 and 49 -- remain at high risk."The trend is that the reporting rates are higher in females compared to males in all age categories," Tom Shimabukuro, the deputy director of the immunisation safety office at CDC, was quoted as saying.Shimabukuro presented the new cases on Wednesday at a meeting of a panel of advisers to the CDC, the report said.Patients with the rare but serious disorder develop blood clots, often in the brain, as well as low levels of platelets -- blood components that promote clotting.The disorder is a "rare, clinically serious and potentially life-threatening condition," Shimabukuro said.Among the 28 confirmed cases, 12 people who developed the disorder had obesity, 7 had high blood pressure, 3 had diabetes, and 3 were taking estrogen, though it is not yet clear whether any of those factors might substantially increase the risk of the disorder, the report said.The CDC and the US Food and Drug Administration had, last month, recommended halting the use of Johnson & Johnson's Covid-19 vaccine, after rare blood clot cases emerged in six recipients.However, the pause was lifted 10 days after a thorough safety review. The agencies had also issued a warning about the potential risks to the vaccine's label, which notes that a connection between the vaccine and the condition is "plausible."Twenty-two of the confirmed cases so far have been in women, and six have been in men. All were adults between the ages of 18 and 59 who received the vaccine before the national pause. (There was also one additional case recorded in a 25-year-old man who participated in the clinical trial), the NYT said.Three people have died and four remain hospitalised, including one who is in intensive care. No new deaths have been documented since last month's meeting, Shimabukuro said.There have been no confirmed cases of the clotting disorder following the Pfizer-BioNTech or Moderna vaccines, which employ a different technology, he added.The roll-out of the single-dose Johnson & Johnson vaccine has been paused in Germany, Denmark, Italy and Canada over the blood clot concerns.--IANSrvt/sdr/