Shoulder Pain Treatment

New York: Ebola virus, which can persist in certain areas of the body, can re-emerge to cause fatal disease, even long after treatment with monoclonal antibodies, according to a study. The study, published in the journal Science Translational Medicine, was conducted using a nonhuman primate model of Ebola virus infection. The research team from US Army Medical Research Institute of Infectious Diseases found that about 20 per cent of monkeys that survived lethal Ebola virus exposure after treatment with monoclonal antibody therapeutics still had persistent Ebola virus infection specifically in the brain ventricular system, in which cerebrospinal fluid is produced, circulated, and contained even when Ebola virus was cleared from all other organs. "Ours is the first study to reveal the hiding place of brain Ebola virus persistence and the pathology causing subsequent fatal recrudescent Ebola virus-related disease in the nonhuman primate model," explained Xiankun (Kevin) Zeng, from the institute. In particular, two monkeys that initially recovered from Ebola virus-related disease after treatment with antibody therapeutics had recurrence of severe clinical signs of Ebola virus infection and succumbed to the disease, Zeng said. Severe inflammation and massive Ebola virus infection were present in the brain ventricular system; no obvious pathology and viral infection were found in other organs. Previous research using nonhuman primate survivors as a model has showed that the virus, despite being cleared from all other organs, can hide and persist in specific regions of immune-privileged organs, such as the vitreous chamber of eyes, the seminiferous tubules of testes, and the ventricular system of the brain reported in this study. "The persistent Ebola virus may reactivate and cause disease relapse in survivors, potentially causing a new outbreak," said Jun Liu, from USAMRIID. Recurrence of Ebola virus disease has previously been reported in human survivors, according to the researchers. For example, a British nurse experienced Ebola virus relapse in the brain, suffering from meningoencephalitis nine months after recovering from severe Ebola virus disease. She had received therapeutic antibodies during the 2013-2016 outbreak in Western Africa, the largest such outbreak to date. In addition, a vaccinated patient who had been treated with monoclonal antibody therapeutics for Ebola virus disease six months earlier relapsed and died at the end of the 2018-2020 outbreak in the Democratic Republic of the Congo. Unfortunately, that case also led to many subsequent human-to-human transmissions Ebola virus causes one of the deadliest infectious diseases known to humankind. It is still a major threat in Africa, and there were three outbreaks in Africa in 2021 alone, according to the World Health Organization. Two vaccines and two monoclonal antibody therapeutics have been approved to prevent and treat Ebola virus disease in recent years. "However, our study reinforces the need for long-term follow-up of Ebola virus disease survivors even including survivors treated by therapeutic antibodies in order to prevent recrudescence. This will serve to reduce the risk of disease re-emergence, while also helping to prevent further stigmatization of patients," Zeng said. (agency) Read More► Obesity Ups Kidney Disease Risk: Study

कोच्चि- केन्या के पूर्व प्रधानमंत्री और आगामी केन्याई चुनावों में संभावित राष्ट्रपति पद के उम्मीदवार रैला ओडिंगा, जो अपनी बेटी के आयुर्वेदिक उपचार के लिए अपने परिवार के साथ केरल में हैं, ने कहा कि वह घर वापस जाते समय दिल्ली में प्रधानमंत्री नरेंद्र मोदी के साथ होने वाली एक बैठक के दौरान दुनिया भर में आयुर्वेदिक तरीके से आंखों का इलाज करने की उस सुविधा को प्रदान करने में मदद करने का अनुरोध करेंगे, जिससे उनकी बेटी को आंखों की रोशनी वापस पाने में मदद मिली है। वह श्रीधरीयम आयुर्वेदिक नेत्र अस्पताल और अनुसंधान केंद्र के प्रमोटरों से मिलने के बाद एनार्कुलम जिले के नेल्लियाकट्टू माना से प्रस्थान पर उनके सम्मान में आयोजित एक समारोह में बोल रहे थे, जहां उनकी बेटी की आंखों की बीमारी का इलाज चल रहा है। उन्होंने यह भी कहा कि अगर उन्हें केन्या का राष्ट्रपति बनने का मौका मिलता है, तो उनकी प्राथमिकताओं में से एक नैरोबी में श्रीधरीयम नेत्र अस्पताल स्थापित करना होगा। वह उस समय भावुक हो गए, जब उन्होंने बताया कि वह अपनी बेटी के इलाज के लिए दुनिया के विभिन्न शहरों में घूमे, मगर उनकी बेटी को कोई फायदा नहीं हुआ। उनकी बेटी रोजमेरी ओडिंगा ने कहा कि जब वह 2019 में पहली बार इलाज के लिए कूथट्टुकुलम आई थीं, तो उनकी आंखों की रोशनी लगभग शून्य थी। उन्होंने कहा, अब मैं अपने फोन पर प्राप्त मैसेज को भी पढ़ सकती हूं और मैं और मेरा परिवार इसके लिए श्रीधरीयम का ऋणी है। 2017 में ट्यूमर के कारण ओडिंगा की आंखों की रोशनी चली गई थी और उनके परिवार ने दक्षिण अफ्रीका, जर्मनी, इजरायल और चीन सहित कई देशों में उनके इलाज के लिए भरसक प्रयास किए। वे 2019 में पहली बार श्रीधरीयम आए, क्योंकि उन्होंने इसकी आयुर्वेदिक नेत्र देखभाल सुविधाओं के बारे में सुना था। श्रीधरीयम में मुख्य चिकित्सक नारायणन नंबूदिरी और उनकी टीम के तहत उनका उपचार शुरू किया गया। चार महीने के भीतर, उनकी आंखों की रोशनी वापस आ गई और वह वापस केन्या चली गईं। अब, वह श्रीधरीयम को धन्यवाद देने और अपने आगे के उपचार के लिए अपने परिवार के साथ फिर से कूथट्टुकुलम आईं हैं। उनका परिवार 7 फरवरी, 2022 को यहां आया था और वे यहां 5 दिनों तक रहे और अब पूर्व पीएम दिल्ली के लिए रवाना हो गए हैं, वहीं उनकी बेटी 28 फरवरी तक इलाज के लिए श्रीधरीयम में ही रहेंगी। (एजेंसी) यह भी पढ़े► मेडिकल के छात्र अब क्षेत्रीय भाषा में लेंगे 'चरक शपथ'

While early treatment has been key to defeating cancer, Covid-induced lockdowns, fear and travel restrictions forced many patients to delay their treatment during the last two years of the pandemic, said experts ahead of the World Cancer Day (February 4). With the increasing burden of Covid patients, straining hospitals and healthcare workers, other diseases were neglected. In many hospitals, the OPDs were shut and surgeries were put on hold. According to a study published in the journal Lancet Oncology in May last year, between March 1 and May 31, 2020, the number of new patients registered decreased to 54 per cent, patients who had follow-up visits decreased to 46 per cent, chemotherapy decreased to 37 per cent. "During these two years of the pandemic, what we have observed is that many newly-diagnosed cancer patients in 2020 avoided hospital visits and thence the treatment, or shifted to alternative treatment modalities," Manish Bhushan Pandey, Senior Consultant, Radiation Oncology, Action Cancer Hospital, Delhi, told IANS. Pandey noted that with the delay in treatment they reached an advanced stage and lost the opportunity of cure. According to a survey by the American Cancer Society Cancer Action Network (ACS CAN), nearly one in four cancer patients said the pandemic has made it more difficult to contact their providers with questions about their healthcare needs, and one in five said they are worried their cancer could be growing or returning due to delays and interruptions caused by the Covid-19 outbreak. "We do not advise any delay in cancer treatment due to the present Covid situation as the disease may progress to a higher stage which may make the disease incurable," Pandey said. "The patients who are undergoing active treatment should continue their chemotherapy and radiotherapy provided they are in good general condition, not suffering from Covid related complications with adequate setup and infrastructure in the hospital," he added Further, the pandemic also led to economic losses due to loss of jobs. This also affected cancer patients, as people could not afford treatment. "Covid-19 has shone a spotlight on the barriers to affordable healthcare that cancer patients have long faced," said Nitesh Rohatgi, Senior Director of Medical Oncology at Fortis Cancer Institute in Gurugram. The experts advised cancer patients to take a high protein diet as they are low on immunity levels. Vaccines have shown to be safe in cancer patients. Besides getting vaccinated, they must avoid crowded places, maintain proper hand, social distancing, respiratory and lavatory hygiene and wear masks at all times, they said. "Please remember that all the healthcare establishments are taking all precautions for the safety of their cancer patients so please don't be afraid and don't ignore your symptoms and keep on getting treatment for cancer," Pandey said. Read More► How Omicron Escapes From Antibodies

Ayurveda defines cancer as a chronic imbalance of tridosha (pathophysiological entity), datus (tissue), and triguna (mental nature) and can be treated without side effects. In Ayurvedic concept, according to 'Charaka' and 'Sushruta Samhitas', cancer is described as inflammatory or non-inflammatory swelling and referred to as 'Granthi' (minor neoplasm) or 'Arbuda' (major neoplasm). The nervous system (Vata or air), the venous system (Pitta or fire) and the arterial system (Kapha or water) are three basic elements of Ayurveda and very important for the normal functioning of the body. How Cancer Spread? As a cancerous tumor grows, the bloodstream or lymphatic system can carry cancer cells to other parts of the body. In this process, cancer cells can develop into new tumors. This is known as metastasis. One of the first places where cancer often spreads is the lymph nodes. The lymph nodes are small, bean shaped organs that help fight infection. They are grouped in different parts of the body, such as the neck, groin, and armpits. Cancer can also spread to remote parts of the body through the bloodstream. These parts may include bone, liver, lungs, or brain. Even if the cancer spreads, it is named after the area where the cancer started. For example, if breast cancer has spread to the lungs, it is called metastatic breast cancer, not lung cancer. Types of Cancer Doctors classify cancers based on where they occur. Four main types of cancer are here: Carcinoma: Cancer begins in the skin or the tissue that covers the surface of internal organs and glands. Carcinomas usually form solid tumors. They all are the most common type of cancer. The examples of carcinoma include breast cancer, prostate cancer, colorectal cancer, and lung cancer. Sarcoma: Sarcoma begins with the tissues that support and connect the body. Sarcomas can occur in fat, muscle, nerves, tendons, joints, blood vessels, lymphatic vessels, cartilage, or bone. Leukemia: Leukemia is a cancer of the blood. Leukemia begins when healthy blood cells change and become uncontrollable. The four main types of leukemia are acute lymphocytic leukemia, chronic lymphocytic leukemia, acute myelogenous leukemia, and chronic myelogenous leukemia. Lymphoma: Lymphoma is cancer that forms in the lymphatic system. The lymphatic system is a network of blood vessels and glands that help fight infection. There are two main types of lymphoma. Hodgkin's lymphoma and non-Hodgkin's lymphoma. Causes of Cancer There can be various causes for cancer, some of the common reasons include: DNA damage or mutations resulting in damage to genes involved in cell division Genetic predisposition Carcinogens such as tobacco Asbestos Arsenic Radiation Ultraviolet rays and automobiles Exhaust gases Cigarette smoking Cigar smoking Passive smoking and chewing tobacco Alcohol use and obesity Lack of physical activity Sunlight and excessive exposure to ultraviolet light Exposure to X-ray radiation Gamma rays Cell phones and cell phone towers Symptoms of Cancer Fever Fatigue Pain Unusual bleeding Nagging cough Indigestion problems or trouble swallowing Unexplained weight loss Skin changes Cancer Treatment in Ayurveda Ayurvedic cancer treatment is very profound and holistic in its approach. Ayurveda treats illness according to the specific nature of the patient, the aggravated bodily energies involved, and the bodily tissues that are affected. The treatment does not only focus on the area of ​​the malignancy but on the entire system, as the entire organism must return to harmony so that the disease is treated permanently and does not recur elsewhere. The body must be cleansed of toxins that cause cells to attack the body. Treatment includes the administration of herbs to cleanse the blood along with the adoption of a detoxifying diet. Circulatory-stimulating herbs are also prescribed to promote circulation, change blood stagnation, increase efficient elimination of toxins, and help heal tissues. Herbs and minerals that restore immunity are administered to increase the strength of weakened patients. Important part of the treatment is the relaxation of the mind. Suppression of emotion or emotional stagnation is a significant causal factor and a barrier to effective treatment of this condition. The patient needs to heal himself at the deepest level of his individuality. Meditation, counseling, yoga, pranayama, and the study of spiritual philosophy are recommended to support this aspect of personal healing. Ayurvedic treatment Ayurvedic holistic methods for cancer treatment include: Abstinence from foods and lifestyle that cause tridosha (vata, pitta, kapha) imbalance, Elimination of toxins through Panchakarma, Restoration of healthy functions of jatharagni (digestive power), Rejuvenation through rasayanas, Ayurvedic preparations can act as an adjuvant or adjunctive therapy along with chemotherapy or radiation therapy. It is also of great help in postoperative care, Ayurvedic medicines help minimize the side effects of these therapies. Immunotherapy: Immunotherapy is one of the effective cancer treatment therapies in which the body's natural defences are stimulated to fight cancer. This therapy works in either of two ways: it stops the growth of cancer-causing cells or slows the growth of cancer cells. Immunotherapy drugs are constantly evolving and are accepted by cancer patients as they have less well-known reactions or side effects compared to chemotherapy and radiation. Cancer Prevention Doctors have identified several ways to reduce cancer risk, including: Give Up Smoking: Quit smoking if you smoke. If you don't smoke, don't start. Smoking is reason of several types of cancer, not just lung cancer. Quitting smoking now can reduce your risk of cancer in the future. Avoid Exposure to Excessive Sunlight: The sun's harmful ultraviolet (UV) rays can increase the risk of skin cancer. Stay in the shade, wear protective clothing, or apply sunscreen to limit exposure to sunlight. Eat A Healthy Diet: Choose a diet rich in fruits and vegetables. Choose whole grains and lean proteins. Limit your intake of processed meats. Exercise Most Days of The Week: Regular exercise helps reduce the risk of cancer. Do atleast 30 minutes of exercise most days of the week. If you don't exercise regularly, start slowly and exercise for at least 30 minutes. Keep A Healthy Weight: Being overweight or obese can increase the risk of cancer. Strive to achieve and maintain a healthy weight by combining a healthy diet with regular exercise. If You Choose to Drink, Drink Moderate Alcohol: If you choose to drink alcohol, drink it in moderation. For healthy adults, this means up to 1 cup a day for women and up to 2 cups a day for men. Schedule A Cancer Screening Test: Talk to your doctor about what type of cancer screening is best for you based on your risk factors. Talk to Your Doctor About Immunity: Certain viruses increase the risk of cancer. Immunization can help prevent viruses such as hepatitis B, which increases the risk of liver cancer, and human papillomavirus (HPV), which increases the risk of cervical and other cancers.