London: A team of researchers, led by those of Indian-origin, has in a breakthrough developed a single gene therapy injection that could dramatically reduce the bleeding risk faced by people with haemophilia B.
Haemophilia B is a rare and inherited genetic bleeding disorder caused by low levels of the factor IX (FIX) protein, needed for forming blood clots that help prevent or stop bleeding.
The gene responsible for making FIX protein is located on the X chromosome, so the severe form of haemophilia B is much more common in men.
Currently, patients with haemophilia B need to inject themselves regularly usually weekly with recombinant FIX, that is, regular replacement therapy to prevent excessive bleeding. Despite advances in treatment, patients may continue to see debilitating joint damage.
But the new type of adeno-associated virus (AAV) gene therapy candidate called FLT180a, developed by researchers from University College London treats severe and moderately severe cases of the condition.
The study, published in the New England Journal of Medicine, showed that one-time treatment with FLT180a led to sustained production of FIX protein from the liver in nine of 10 patients across four different dose levels, removing the need for regular replacement therapy.
"Removing the need for haemophilia patients to regularly inject themselves with the missing protein is an important step in improving their quality of life," said lead author Professor Pratima Chowdary, Royal Free Hospital at UCL Cancer Institute.
AAV gene therapy works by using a packaging from the proteins found in the outer coat of the virus, to deliver a functional copy of a gene directly to patient tissues to compensate for one that is not working properly.
Newly synthesised proteins are released into the blood and a one-time infusion can achieve long-lasting effects.
Patients needed to take immunosuppressive drugs over several weeks to several months to prevent their immune systems from rejecting the therapy.
While the treatment was generally well tolerated, all patients experienced some form of adverse events, with an abnormal blood clot in one who received the highest FLT180a dose and had the highest levels of FIX protein.
In nine out of the 10 patients, the treatment led to a sustained increase in FIX protein production, which led to a decrease in excessive bleeding. They also no longer required weekly injections of FIX protein.
After 26 weeks, five patients had normal levels of FIX protein, three had low but increased levels, and one patient treated at the highest dose had an abnormally high level. (Agency)
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No matter where you live, in India or elsewhere, doctors are valued for their skills, knowledge, trust and communication.
According to one study, meaningful doctor-patient communication is a crucial clinical function in building a medical-patient therapeutic relationship and is the basis of the art of medicine.
The impact on medical care results is what defines the doctor-patient relation's importance. The quality of doctor-patient communication and their relationship strongly indicate quality medical care, which plays an essential role in providing general medicine with medical care.
Let us learn more about getting more patients with India’s biggest Ayurvedic doctors platform:
How NirogStreet's Partnership Program Helps Doctors With Potential Patients?
NirogStreet's partnership program seeks to increase the number of online consultations and community education for Ayurveda doctors. This program offers technical assistance, Virtual Inventory, and marketing support for your Ayurveda clinic. Live-streamed community learning and personal earning are the primary focus of the program.
Why Do I Need It?
Boosts Consultation: Especially Online
Enhances current practice
Cuts down on administrative cost
Cuts down courier charges and hassles
It makes your clinic technologically
What Do I Get in This Program?
Visibility: Web Profile, Business listings, Your Virtual Business Card
Social Media Reach: Done-for-you Content
Exclusive Webinars: Clinical, Non-Clinical
VaidyaTool: Patient Management System
Recognition: Success Story, Webinar participation, Promotion in the largest
Community of doctors
Inventory of 1000+ Ayurvedic medicines from reputed brands
Free home delivery of medicines to you and your patients (Pan India)
Factor Given Below Are Help Increase Patients in Your Clinic
An effective marketing strategy has proven to be a critical factor in your clinic's long-term results and sustained growth. These healthcare clinic marketing methods have achieved success in the current time.
Get Yourself A Mobile Friendly Website
How does a mobile-friendly website function? Well! There are several factors that makes your website mobile friendly i,e.
Pagespeed insights: tracking overall page speed on mobile and desktop however, it suggest improvements as well.
Mobile-Friendly Test: shows website’s mobile friendly nature in ‘Yes’ or ‘No’.
Test My Site: Evaluating your website for mobile and desktop devices.
A mobile-friendly web site works on all devices and displays well on them, including tablets. Most people visiting your website will abandon it if they can't find their desired content quickly.
Social Media is The Power
Becomig active on Social media can bring thousands or even tens of millions of eyes to updates, educational content, marketing campaigns, and other important information. Social media can be an essential driver of patient acquisition and retention of existing ones.
Being an active doctor on social media:
Enhance patient engagement by allowing you to have conversations that you might not usually have with your patients
Continue activation scale your reach and exposure will increase
Optimize your search engine optimization (SEO)
Building your online reputation
Encourage team-building among your clinic or hospital staff
Build Authentic Relationships
Although inter-personal relationships skills are important, they depend on the context where communication takes place. Consultations may not be relevant to them.
Organizations can develop and sustain strong, long-lasting relationships with their patients. This will allow them to anticipate patient needs better and provide proactive care that results in better health outcomes and a better customer experience.
Ask Successfully Treated Patients For Reviews
Your exceptional services should be made known to the public through patient feedback. This will help you understand your work's strengths and weaknesses and increase your organic impact on potential clients. Patients who have a positive experience at your clinic because of your consultation and treatment will be more likely to share that with their friends and families.
Ask your patients to review the given services
Send them a survey form regarding improvements
Ask them to suggest what is missing or your expectation of medical services
For doctors who have most of their customers or patients in their community, it's vital for them and others to create a sense of community within the area and communicate with each other more deeply.
However, the NirogStreet app has numerous communities formed by expert Ayurvedic doctors from across the country, which you can join to be a part of. Also, you can make your community of doctors. This could prove highly rewarding as it allows you to grow your reach both offline and online.
FAQ’s (Frequently Asked Question)
Q. How can I get more patients in my clinic in India?
Ans. Online reviews are an effective way to draw new patients and expand your practice. Encourage patients to write reviews online. You can encourage your patients to share their feedback online by sending them a follow-up message thanking them for their visit.
Q. How can I grow my clinic?
Ans. Patient Feedback And Reviews. Feedback from patients is a key component in getting your extraordinary services out to the public. Take networking seriously. Your web presence can be improved. Make use of social media.
Q. How do I promote my clinic on Google?
Ans. Go to the link: https://www.google.com/intl/en_us/business/ and start a Google MyBusiness account. Overview, Business Profile, Website buttons. Click on overview to begin. Click on overview to enter the name of the clinic.
Q. Do doctors have their own Google?
Ans. Doctors are increasingly using online search engines to find information. 68% use Google most frequently, and more than half do so at least once daily for professional purposes. The most frequent searchers among doctors are the oncologists, and 45% use search engines at least four times daily.
Are you an Ayurveda doctor? Be a part of the NirogStreet Doctor Community
The presentation has always been a crucial element irrespective of the profession, and if you are new in the business, it shouldn't be taken lightly.
For some new doctors, there may be some doubt about setting up an account on Facebook, Instagram, and LinkedIn and attracting new clients from these social media sites. But, as more doctors realize there are more new potential clients outside their clinic and If you're not engaging on the internet then your business is missing the chance of attracting new patients?
New doctors find it challenging to seek digital marketing professionals for their medical practice. And NirogStreet, a tech-driven platform for more than 1,00,000 doctors, is now incorporating necessary steps to make Ayurveda mainstream by promoting and empowering new doctors with the latest trends & technology to harness their online presence leading to potential patients across the world.
Here are some simple ways for your healthcare marketing & for your online presence:
Target Keyword on Your Website
The way you target symptoms to reach diseases and keyword targeting will help you keep your posts on track and optimize your posts to boost their visibility on the results of google searches and social media.
You've probably realized that it's crucial not just to create a functional site; you must also have a site that search engines can find. One method of doing this is to include relevant keywords within your site's text.
These are the keywords you want to show up for your target audience or patients seeking your services. For instance, if you're a primary care doctor located within New Delhi, you may consider including "New Delhi primary care doctor" or "New Delhi doctor's office" on your site.
Be sure to include them in the text of your website, as well as in meta descriptions and page titles, as well as in the image alt tags, as well as in your blog articles.
Utilize Google My Business
Google Business is the largest platform for obtaining online appointments for doctors. And it's free, but you must place your Google Maps in the first three of Google Search Engine.
Google My Business allows you to see your clinic on local listings and maps. Every doctor should sign up for a Google My Business account, which is easy and cost-free. It is also possible to include clinic photos, addresses, service hours, time of operation, contact number, and address of the hospital or clinic.
Patients can also send messages or make an appointment, and doctors can add educational or testimonial videos for patients on Google business. The most intriguing aspect of Google enterprise is that we can ask patients to write reviews of the services they received, and a positive review works as word of mouth for other patients. Let's learn more about patient review in the next point given below.
A reputable online presence is incomplete without reviews because most patients seeking your clinic visit google rating before consultations. This means that potential patients will most likely believe the reviews posted online, and it's crucial for you to concentrate on getting positive reviews.
Reviews can encourage interaction between customers and your website. Ensure that you encourage happy content customers to check out your reviews site and leave comments. Be sure to ensure they are happy by responding to each review, avoid negative reviews and if possible seek out those patients and ask them to clarify their problem.
One out of 20 searches on Google daily is linked to health care. They are also more likely to visit sites that have excellent scores. Why not concentrate on creating a robust online presence? The NirogStreet partnership program will help you achieve this and much more, click here to read more.
Making a solid, precise profile on listing websites for businesses such as Justdial, Sulekha & others can be highly beneficial to expanding the visibility of your business. Local Search Engine offers local search-related services to its users.
NirogStreet for doctors includes various important information such as the services we offer, the clinic's location, hours of operation, address, contact information, and pictures. This information can benefit patients who want to get in touch with the relevant doctors.
Patients can also provide comments or feedback on the services offered, which could boost the popularity, transparency and confidence among patients. Making a profile on business websites will increase your visibility on Google search results bringing prospective patients to your clinic.
Social Media Pages
Creating profiles on social media platforms such as Facebook, Instagram, Twitter, LinkedIn & Youtube is essential to gain the desired fame and expand the reach of your business. Social media is among the most cost-effective marketing strategies to improve your company's visibility.
Today every doctor must be active on social media platforms. The creation of profiles on social media websites has many benefits, including increased brand recognition, traffic to our website, improved search engine rank and efficiency in conversion, greater patient satisfaction, effective marketing and a good level of loyalty to your business.
Medical professionals can maintain contact with patients or their followers through social media platforms and quickly provide information to people or raise awareness within society on diseases and precautions. Social media is an efficient and results-oriented method to reach the maximum number of patients and increase business growth.
So, even if you are a new doctor, the Partnership program at NirogStreet is all set to boost your online reputation and offer you new clients.
Connect with us now on this no: 9319361976, Let's make Ayurveda the first line of treatment.
FAQs(Frequently Asked Question)
Q. How can I get more patients online?
Ans. Establishing a robust online reputation by considering digital marketing best practices, including building websites and social media sites, keyword targeting, service promotion, business listings, etc. Joining NirogStreet’s partnership programs offers all these benefits along with some more.
Q. How do online clinics work?
Ans. Virtual clinics can be established for each service offered by the hospitals. Patients can be directed to specific web pages to access detailed information regarding consultations. On the other hand, the clinicians have direct face-to-face participation, which is considered an online waiting room for all the services you'd prefer patients to receive.
Q. How do I start an online medical consultation business?
Register in the NirogStreet partnership program.
Download the NirogStreet mobile app and submit your details along with your medical registration certificate.
Setup Online Practice. Once your details are verified by NirogStreet Team, you are ready to consult patients online or can set up your Online Practice.
Invite Patients. You will be assigned a unique ID from NirogStreet.
Q. How do you promote a health clinic?
Ans. Social media has become integral to hospital or clinic marketing, and its importance is growing yearly. Using your social media profiles, you can connect with thousands of prospective patients and patients who have had positive experiences at your hospital to share their recommendations on your Twitter and Facebook pages.
Q. How do I promote my clinic on Google?
Get a website
Get the Seo part done
Begin content marketing
Initiate paid search
Create social media profiles
Q. What app do doctors use for telemedicine?
Ans. NirogStreet is one of the popular telemedicine apps in the Ayurveda ecosystem. Some of the key features and services it provides include a comprehensive medical directory, online consultations, and booking of appointments online. Avail all the benefits by registering yourself in NirogStreet’s partnership program.
Q. Is online doctor consultation legal in India?
Ans. There is nothing illegal about online medical consultations online; however, such talks should not be followed by giving prescriptions. Also, a general suggestion can be offered; however, it is impossible to prescribe any medication, and it is not allowed in India or most parts of the globe.
Are you an Ayurveda doctor? Be a part of the NirogStreet Doctor Community
People who regularly fast are less likely to experience severe complications from Covid-19, suggests a study.
Intermittent fasting has previously shown to have a host of health benefits, including lowering the risk of diabetes and heart disease.
The findings, published week in BMJ Nutrition, Prevention & Health, showed that Covid patients who practised regular water-only intermittent fasting had lower risk of hospitalisation or dying due to the virus than patients who did not.
"Intermittent fasting has already shown to lower inflammation and improve cardiovascular health. In this study, we're finding additional benefits when it comes to battling an infection of Covid-19 in patients who have been fasting for decades," said Benjamin Horne, director of cardiovascular and genetic epidemiology at Intermountain Healthcare in the US.
In the study, researchers identified 205 patients who had tested positive for the virus between March 2020 and February 2021 -- before vaccines were widely available.
Of these, 73 said they regularly fasted at least once a month. Researchers found that those who practised regular fasting had a lower rate of hospitalisation or death due to coronavirus.
"Intermittent fasting was not associated with whether or not someone tested positive Covid-19, but it was associated with lower severity once patients had tested positive for it," Horne said.
While Horne said that more research is needed to understand why intermittent fasting is associated with better Covid outcomes, he said it's most likely due to a host of ways that it affects the body.
For example, fasting reduces inflammation, especially since hyperinflammation is associated with poor Covid-19 outcomes. In addition, after 12 to 14 hours of fasting, the body switches from using glucose in the blood to ketones, including linoleic acid.
"There's a pocket on the surface of SARS-CoV-2 that linoleic acid fits into -- and can make the virus less able to attach to other cells," he said.
Another potential benefit is that intermittent fasting promotes autophagy, which is "the body's recycling system that helps your body destroy and recycle damaged and infected cells", Horne added.
Horne stressed that these results are from people who have been practising intermittent fasting for decades -- not weeks -- and that anyone who wants to consider the practice should consult their doctors first, especially if they are elderly, pregnant, or have conditions like diabetes, heart, or kidney disease.
Researchers also stressed intermittent fasting shouldn't be seen as a substitute for Covid vaccination. (Agency)
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एक अध्ययन के अनुसार, 69 फीसदी लोगों ने कोविड संक्रमण से पहले सिरदर्द की शिकायत की है, यह इस बीमारी का प्रमुख लक्षण बन गया है।
किंग्स कॉलेज लंदन के शोधकर्ताओं ने जोई कोविड लक्षण अध्ययन ऐप के डेटा का विश्लेषण किया और स्थिति के पहले लक्षणों में से एक के रूप में सिरदर्द पाया।
एक्सप्रेस डॉट को डॉट यूके की रिपोर्ट के अनुसार, यह बुखार, खांसी और हानि या स्वाद और गंध में बदलाव जैसे अन्य क्लासिक कोविड लक्षणों की तुलना में अधिक सामान्य है।
अध्ययन में बताया गया है कि कुछ कोविड रोगियों को प्रारंभिक संक्रमण की तुलना में अधिक समय तक सिरदर्द के साथ देखा गया, यह संकेत भी लंबे कोविड के लिए एक विशेषता है।
अध्ययन के अनुसार, हमारे डेटा से पता चलता है कि ये सिरदर्द अक्सर आते हैं और जाते हैं, लेकिन शुक्र है कि वे समय के साथ धीरे-धीरे कम हो जाते हैं।
हालांकि यह दर्दनाक लक्षण बच्चों में कम आम लगता है, कोरोनोवायरस सिरदर्द सभी आयु समूहों में देखा जाता है।
अध्ययन के अनुसार, इसलिए, हालांकि कोविड -19 वाले कई लोग सिरदर्द का अनुभव करते हैं। जरूरी नहीं है कि सिरदर्द वाले अधिकांश लोगों को कोविड -19 नहीं होगा। थकान और गंध की कमी के साथ सिरदर्द कोविड को संकेत दे सकता है।
रिपोर्ट में कहा गया है कि अन्य लक्षण जो वायरस की दिशा को भी इंगित कर सकते हैं, उनमें गले में खराश, बुखार, मांसपेशियों में असामान्य दर्द और लगातार खांसी और चक्कर आना शामिल हैं।
यह भी पढ़े► कोविड रोगियों ने माना स्वस्थ्य होने में योग ने की मदद
People infected with Covid-19 had a roughly 25 per cent increased risk of developing a psychiatric disorder in the four months following their infection, compared with those who had other types of respiratory tract infections, finds a study.
Researchers at Oregon State University in the US found that Covid patients had a 3.8 per cent rate of developing a psychiatric disorder compared with 3.0 per cent for other respiratory tract infections. The 0.8 per cent difference amounts to about a 25 per cent increased relative risk.
The team looked specifically at anxiety disorders and mood disorders and found a minor but significant increase in risk for anxiety disorders and no change in risk for mood disorders.
The results speak to the need for both patients and health care providers to be more proactive when it comes to addressing mental health concerns following Covid infection, said Lauren Chan, doctoral student in nutrition in OSU's College of Public Health and Human Sciences.
"For people that have had Covid, if you're feeling anxiety, if you're seeing some changes in how you're going through life from a psychiatric standpoint, it's totally appropriate for you to seek some help," Chan said.
For the study, published in the journal World Psychiatry, researchers included data of 46,610 Covid-19 positive individuals and control patients who were diagnosed with a different respiratory tract infection so they could compare how Covid specifically affected patients' mental health.
They looked at the rate of psychiatric diagnoses for two time periods: from 21 to 120 days after patients' Covid diagnosis, and from 120 to 365 days after diagnosis, limited to patients with no previous mental illness.
When patients leave a doctor's office, sometimes care stops there, but Chan recommended that providers consider calling in two weeks for a check-in.
"I don't want to say that every single person who gets Covid is going to have this type of problem, but if you start to have concern for yourself or a family member, it's not unheard of. You should definitely seek care for yourself or others around you," Chan said.
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