Singapore, Aug 19 (IANS) People who were infected with SARS in 2003 and recovered are able to produce antibodies that can potentially neutralise all known Covid-19 variants of concern, scientists have found.The findings, published in The New England Journal Of Medicine, could pave the way for the development of a booster jab, which may involve targeting the SARS-CoV-1 virus responsible for the SARS epidemic in 2003, the Strait Times reported.A team from the Duke-NUS medical school and the National Centre for Infectious Diseases (NCID), found that the antibodies can also tackle other potential animal coronaviruses, offering a broader spectrum of protection for future variants and coronaviruses.Among the coronavirus family, one viral sub-group relies on the ACE2 molecule -- a protein found on the surface of many cell types -- to enter human cells. Neutralising antibodies are able to prevent the viral spike protein from binding with the ACE2 molecules in human cells."Both SARS-CoV-1 and the SARS-Cov-2 virus, which causes Covid-19, belong to this group, as well as a number of coronaviruses circulating among animals such as bats, pangolins and civets," Professor Wang Linfa from the Duke-NUS Emerging Infectious Diseases (EID) programme was quoted as saying."Collectively, this group of viruses is known as the sarbecovirus, which has the potential to jump from animals to humans, and could start the next pandemic, although the exact route of transmission still remains unknown," he added.The SARS-CoV-1, SARS-CoV-2 viruses, and the sarbecoviruses have similar antibody-binding sites, which can be targeted by a pan-sarbecovirus neutralising antibody to prevent infection.For the study, the team recruited eight people who recovered from SARS-CoV-1, 10 healthy people and 10 people who recovered from Covid-19 and compared the immune response of the three groups before and after they were vaccinated with the Covid-19 vaccine.Before getting vaccinated, people who recovered from SARS had detectable neutralising antibodies against the SARS-CoV-1 virus, but had little to no antibodies against the SARS-CoV-2 virus, Dr Wanni Chia, a research fellow at the Duke-NUS EID programme was quoted as saying.But after taking two shots of the Pfizer Covid vaccine, they displayed high levels of neutralising antibodies against both viruses, and a broad spectrum of antibodies against 10 sarbecoviruses that were examined, she noted.The team now aims to develop a vaccine booster to increase protection for the Covid-19 variants, and potential SARS-CoV-3 or SARS-CoV-4 disease, the report said.--IANSrvt/vd
New Delhi, Aug 18 (IANS) As many as 41 per cent of surveyed Delhi households say that they have one or more members who are currently down with flu-like symptoms.The findings of the survey by Local Circles also indicate that 22 per cent of Delhi households are fully impacted with it, which means all members are having such symptoms while 19 per cent have only 1 member so far and it is likely that more members may develop symptoms in the days to come. However, 59 per cent of citizens have indicated that they do not have anyone in their households with the flu-like symptoms, the survey said. Many Delhi residents in the last 7 days have reported that one or more members in their family are struggling with Covid-like symptoms i.e. fever, runny nose, fatigue. Many are also getting a RT-PCR test done only to find later post doctor consultation that they are Covid-negative and had gotten under the influence of some kind of viral infection or seasonal flu. Doctors across hospitals are saying that 80 per cent of such cases were seasonal flu and 20 per cent were of Swine Flu. The Covid-19 test positivity rate in the national capital is currently less than 0.1 per cent. Residents of NCR cities i.e., Noida, Gurugram, Ghaziabad, and Faridabad have also reported rising instances of similar Covid-like symptoms. --IANSsan/vd
London, Aug 16 (IANS) Covid-19 and flu vaccines could eventually be mixed into one injection to save time and make future booster programmes more convenient, says a vaccine producer in the UK.Vaccine Manufacturing and Innovation Centre (VMIC) CEO Matthew Duchars said that the facility is looking at combining the two for future roll-outs."It will save a lot of time and it would be a lot more convenient to just give one shot, so it is something that we and vaccine developers and producers will be looking at," Duchars was quoted as saying by The Telegraph."Let's say we do need to give a seasonal vaccine, and people need one shot for flu, and one shot for Covid and another for something else... If you can put them all into one, then that's obviously preferable," he added.As per the report, the Oxford-based VMIC was announced in 2018 as the UK's first-ever vaccine-making hub and was due to open in 2022.The government said at the time it would invest 66 million euros in the centre, but it had been granted 215 million euros in funding by March and was fast-tracked to help in the fight against Covid-19.It was founded by the University of Oxford, the Imperial College London, and the London School of Hygiene and Tropical Medicine, the report said.Once up and running, the VMCI will churn out 70 million doses in as little as four months -- nearly 600,000 doses a day, it added.--IANSvc/vd
What happens inside our bodies is reflected on the outside and hormonal disbalances are one of the most prominent outbreaks that we can see on the skin. Our hormones keep changing and lose their balance due to age, and other factors that cause problems on the outside and one such problem is hormonal acne.
Some people experience them during their periods, or pregnancy because those are the times when your body goes through major hormonal changes and hence the acne starts showing up. But how to get rid of this acne? Is there a permanent solution?
While we can't say if these solutions are permanent, Paridhi Goel, Founder of Love Earth, Herbal and Organic Skin Care Brand shares definitely worth a try tip to help you reduce acne formation by manifolds.
Also, Read This► Skincare Hacks With Superfoods
1. Start with washing your face multiple times because the dirt particles sitting on your face lead to hormonal acne. But if the outer layer of your skin is clean, the chances of getting acne reduces. Use a very mild face wash, and wash it at least 2-3 times a day. Keeping your face clean and dirt-free will really help in reducing dirt settling on the skin, clogging the pores, and leading to acne formation.
2. Stay hydrated at all times. Drink as much water as prescribed so that your skin is hydrated as well. Also include green tea in your daily routine because it works internally and decreases acne formation on your face. It is a magic potion that works beautifully on the inside.
3. Start using Fuller's Earth (Multani mitti pack) because it cools your skin. You can find it easily at any departmental store. All you need to do is mix it with some rose water and apply the pack to your face. Apply it 2-3 times a week because it works great on hormonal acne.
4. Always use less moisturizer because your skin must be oily already. And use a gel-based moisturizer with a pea-size application.
5. Use retinol or retinoids, both derived from Vitamin A and great for the skin. It removes dead skin which causes hormonal acne and also increases skin cell turnover. They clean the pores and let the medication penetrate through the skin for better results.
6. Tea Tree is a holy grail product for all sorts of acne. It decreases inflammation on the skin that causes acne. Just take a drop of oil and apply it to the active acne. Don't use the same finger on every acne to prevent germs transfer. The quantity has to be just one drop because tea tree oil dries the skin too fast and you don't want that. So, go light on the quantity but use it every day, preferably in the night hours.
7. Talk to your gynaecologist and consult them about the hormonal disbalance that is causing the acne. Once you figure out the reasons for disbalance, you can start your medication accordingly and that acne will disappear eventually.
8. Always wear sunscreen whenever leaving the house. Your skin needs protection to stay away from more acne.
9. Don't wear makeup that clogs your pores. It is advisable to avoid makeup as much as possible because the products that clog your pores will lead to more acne formation.
10. Hormonal acne is unavoidable but still controllable. You can use these home remedies and make your skin look better this season!
Read More► Steam Your Face for Glowing Skin
Chennai, Aug 10 (IANS) The Tamil Nadu BJP will train 26,000 volunteers and deploy them to the villages of the state to curb the Covid-19 pandemic. This was announced by party state president K. Annamalai on Tuesday.The party is gearing up for this massive deployment of health volunteers in order to curb a possible third wave of the Covid-19 pandemic. The state president said that these volunteers would be deployed at 13,000 villages in the state.Annamalai, while addressing a state-level health volunteers workshop at Tindivanam, said that the DMK which was opposed to the central government is now praising the work done by the central government to contain Covid-19.The vaccination programmes of the central government have also drawn praise from parties like DMK which were opposing the BJP and the central government day in and day out, the BJP state president told the party cadres.BJP's former national secretary H. Raja, former state president C.P. Radhakrishnan and Co-in charge Sudhakar Reddy also spoke on the occasion.The party has already formed a 17-member committee to prepare itself for the ensuing elections to the rural bodies which is to be announced soon. The polls will take place in nine newly carved out districts of the state and the saffron party is working at the grassroots level in these districts to make a mark in the rural body polls as it is buoyed by the success of electing 4 MLAs in the recent assembly elections.--IANSaal/skp/
New York, Aug 9 (IANS) Healthy young people diagnosed with Covid-19, regardless of their symptom severity, have problems with their nervous system when compared with healthy control subjects, according to a study.The research, published in The Journal of Physiology, showed that among people who were recently diagnosed with Covid-19, the sympathetic nervous system -- which oversees the fight-or-flight response -- seems to be abnormal (overactive in some instances and underactive in others).The sympathetic nervous system plays an important role in exercise responses, the digestive system, the immune function, among others."The impact of this alteration in fight-or-flight response, especially if prolonged, means that many processes within the body could be disrupted or affected," said researchers including Abigail S.L. Stickford, Department of Health and Exercise Science, at the Appalachian State University in North Carolina, US."These results are especially important given the emerging evidence of symptoms like racing hearts being reported in conjunction with 'long Covid'," they added.The team conducted a series of tests to show that young adults recovering from SARS-CoV-2 have elevated resting sympathetic activity, but similar heart rate and blood pressure, compared with control subjects.The survivors of SARS-CoV-2, the virus causing Covid-19, also exhibit suppressed sympathetic nerve activity and pain perception during a cold pressor test compared with healthy controls.Further, these individuals display higher sympathetic nerve activity throughout an orthostatic challenge, as well as an exaggerated heart rate response to orthostasis."If similar autonomic dysregulation, like that found here in young individuals, is present in older adults following SARS-CoV-2 infection, there may be substantial adverse implications for cardiovascular health," the researchers said.The study also noted limitations that the researchers do not know how Covid-19 subjects' nervous system activity "looked like" before they were diagnosed with Covid-19.However, these findings are consistent with the increasing reports of long-Covid symptoms pertaining to problems with the fight-or-flight response, they said.--IANSrvt/vd