New York: Longer and more frequent daytime napping among older adults maybe linked with poor cognitive performance - a sign of Alzheimer's disease, claims a study.
In the study conducted over 1,000 adults with an average age of 81, published in Alzheimer's and Dementia: The Journal of the Alzheimer's Association, longer or more frequent daytime napping in a specific year predicted worse cognitive performance in the following year, and vice versa.
"Daytime sleep behaviours of older adults are often ignored, and a consensus for daytime napping in clinical practice and health care is still lacking," said Peng Li, from Division of Sleep and Circadian Disorders at Brigham and Women's Hospital in the US.
"Our results not only suggest that excessive daytime napping may signal an elevated risk of Alzheimer's dementia, but they also show that faster yearly increase in daytime napping may be a sign of deteriorating or unfavored clinical progression of the disease.
"Our study calls for a closer attention to 24-hour sleep patterns - not only night-time sleep but also daytime sleep for health monitoring in older adults," Li said.
Studies on daytime napping in older adults have had conflicting results, with showing that daytime napping has benefits on acute cognitive performance, mood, and alertness, others have highlighted the adverse outcomes on cognitive performance.
In the current study, the team tested two hypotheses: participants nap longer and/or more frequently with ageing and the changes are even faster with the progression of Alzheimer's; and participants with excessive daytime napping are at an increased risk of developing the disorder.
The participants were provided a watch-like device called Actical, to wear on their non-dominant wrist for up to 14 days. The team identified sleep episodes using a previously validated sleep scoring algorithm that considers wrist activity counts. After napping episodes were identified, the nap duration and frequency were calculated.
Independent of known risk factors for dementia, including age and night-time sleep duration and fragmentation, longer and more frequent daytime naps were a risk factor for developing Alzheimer's dementia in cognitively normal older men and women.
Besides, annual increases in napping duration and frequency were accelerated as the disease progressed, especially after the clinical manifestation of Alzheimer's. Ultimately, the authors describe the relationship between daytime napping and cognition to be a "vicious cycle." (agency)
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Argentina federal police will now effectively use technique of Yoga for stress management of its personnel. Though Yoga has been practiced in this part of globe for last several years, yet in last couple of year, interest in yoga and awareness in Indian culture has increased rapidly. Earlier Yoga and meditation were also taught in some Latin American jails to calm down the convicts.
Embassy of India in Argentina and University Institute of the Argentine Federal Police (IUPFA) will be jointly conducting a workshop on Yoga.
The general objective of this workshop will be to promote the practice of Yoga as a tool to develop physical, mental and emotional well-being, incorporating discipline techniques for stress management.
University Institute of the Argentine Federal Police students, faculty, graduates, and staff; students from the School of Cadets and the School of NCOs and Agents of the Argentine Federal Police can participate in this workshop.
The Ministry of Ayush has been striding forth with establishing the curative values of yoga and integrating yoga with various disciplines to reap societal benefits. Yoga can be of immense benefit to the armed and paramilitary forces.
Yoga is highly effective in enduring tolerance and proves to be immune-modulatory and also helps in augmenting stress hormones and neurotransmitters.
In India a customized yoga packages has been developed for army, air force and navy to tackle high altitude, hot desert and cold desert conditions and submarine and ship conditions.
According to various research, it has been found that āsanas and prānayāms have enabled its application in combating the stress in soldiers and promoting their psycho-physiological fitness.
Also, Read in Hindi► तनाव दूर करने के लिए अर्जेंटीना की संघीय पुलिस योग को अपनाएगी !
Long-term use of over-the-counter painkillers is leading to kidney damage among people, doctors here have warned ahead of World Kidney Day.
World Kidney Day is a global campaign observed annually on March 10. It is aimed at raising awareness about the importance of our kidneys.
Many painkillers are sold without a prescription for reducing pain and inflammation. These include Non-steroidal Anti-inflammatory Drugs (NSAIDs) such as ibuprofen, diclofenac and naproxen.
A combination of drugs, including aspirin, acetaminophen and caffeine, are also easily available and commonly taken by patients for chronic headaches and backaches.
"Not many people realise it, but long-term use of analgesics (painkillers) can lead to a condition called analgesic neuropathy which causes kidney damage. Painkillers don't harm the kidneys in healthy individuals if taken occasionally.
However, taking them too often for a prolonged period, especially as a combination of drugs, can cause severe kidney damage," Dr. Manju Aggarwal, Chief - Medical Services & Chairperson - Nephrology at Artemis Hospital, Gurugram.
Aggarwal added that the threat is even greater in high-risk individuals such as the elderly, diabetics and patients of high blood pressure. Their kidneys can get damaged with even occasional use of painkillers, she noted.
Painkillers lead to kidney damage in many ways, including acute rise in creatinine levels, known as Acute kidney Injury.
There can also be worsening of pre-existing Chronic Kidney Disease in terms of rise in creatinine levels.
Painkillers can also cause a rise in potassium levels in the body. Most patients remain asymptomatic in early stages of kidney disease and the raised creatinine is an incidental finding.
However, in advanced forms of the disease, there can be breathlessness, vomiting, loss of appetite and swelling all over the body.
The doctor said that prevention is always better than cure, so a judicious use of painkillers is advised. These should be taken if absolutely necessary.
"Patients with known kidney disease or those at risk of kidney disease such as the elderly and diabetics should avoid pain killers totally. They should instead switch to paracetamol or opioids for pain control," Aggarwal said.
"If you are taking painkillers regularly and find that your creatinine level is raised, discontinue their use and see a nephrologist immediately," he advised.
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"This is yet another milestone in our fight against Covid-19. Covovax is now WHO approved for emergency use, showing excellent safety and efficacy. Thank you all for a great collaboration," Serum Institute of India CEO Adar Poonawala said.
Covovax has a two-dose regimen and is the ninth to receive emergency use approval from the WHO. However, it is yet to be granted emergency use authorisation (EUA) by the top drug regulator, the DCGI, in India.
The listing aims to increase access particularly in lower-income countries, 41 of which have still not been able to vaccinate 10 per cent of their populations, while 98 countries have not reached 40 per cent, said the global health body.
Covovax was assessed under the WHO EUL procedure based on the review of data on quality, safety and efficacy, a risk management plan, programmatic suitability, and manufacturing site inspections carried out by the Drugs Controller General of India.
The Technical Advisory Group for Emergency Use Listing (TAG-EUL), convened by the WHO and made up of experts from around the world, has determined that the vaccine meets WHO standards for protection against Covid-19, that the benefit of the vaccine far outweighs any risks, and that the vaccine can be used globally, the WHO said in a statement.
The Covovax vaccine, developed by the SII in partnership with the US-based Novavax, is the third India-related vaccines to be approved by the WHO. The other two vaccines are Covishield and Covaxin. Covaxin is India's first indigenous Covid vaccines, while Covishield is Indian version of Britain's AstraZeneca jab.
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आयुष मंत्रालयाने यासाठी तज्ञ गटाची स्थापना करून एएसयू (आयुर्वेद, सिद्ध आणि युनानी) औषधांमध्ये अश्वगंधा (विथानिया सोम्निफेरल) पानांच्या वापराशी संबंधित प्रकरणाची पुन्हा तपासणी करण्याचा निर्णय घेतला आहे.
यापूर्वी, मंत्रालयाने ASU औषधांमध्ये अश्वगंधाच्या पानांच्या वापराविरोधात मार्गदर्शक तत्वे जारी केली होती.
आयुष मंत्रालयाने अश्वगंधा पानांचा वापर प्रतिबंधित केल्याच्या पार्श्वभूमीवर एएसयू औषध निर्मण उद्योगांच्या भागीदारांकडून निवेदने प्राप्त झाली होती.
तसेच, आयुष मंत्रालयाने हितधारकांना एएसयू उत्पादनांमध्ये अश्वगंधाच्या पानांच्या वापराबाबत समस्यांवर चर्चा करण्यासाठी आमंत्रित केले होते. या चर्चेच्या आधारे, मंत्रालयाने तज्ज्ञ गट स्थापन करून अश्वगंधा (विथानिया सोम्निफेरा) पाने वापरण्यापासून परावृत्त करण्यासाठी औषध उत्पादकांना जारी केलेल्या मार्गदर्शक तत्वे पुन्हा तपासून पाहण्याचा निर्णय घेतला आहे.
वैज्ञानिक पुराव्याच्या आधारे एएसयू उत्पादनांमध्ये अश्वगंधाची पाने/अश्वगंधाच्या पंचांगाच्या वापराबाबत तज्ञ गट सरकारला योग्य शिफारसी करेल.
पुढे वाचा► आयुष-64 ची मागणी आता सहज पूर्ण होणार; सीसीआरएएस ने 46 कंपन्यांना तंत्रज्ञान हस्तांतरित केले
The Ministry of Ayush has decided to re-examine the matter relating to the use of Ashwagandha (Withania somniferal) leaves in ASU (Ayurveda, Siddha and Unani) drugs by constituting an expert group to this end.
Earlier, the ministry had issued an Advisory against using the leaves of Ashwagandha in ASU Drugs.
In the wake of Ayush Ministry barring the use of Ashwagandha leaves (vide letter No. L-11011/9/2021-DCC dated 06.10.2021 to the ASU Drugs Manufacturing Association), representations had been received from the ASU Drugs Manufacturing Industry partners.
Also, the Ministry of Ayush had invited the stakeholders to discuss their concerns about the utilization of Ashwagandha leaves in ASU products. Based on this discussion, the ministry has decided to re-examine the advisory issued to the drug manufacturers to refrain from using Ashwagandha (Withania somnifera) leaves by setting up an Expert Group.
The Expert Group will make appropriate recommendations to the Government of India on the use of Ashwagandha leaves/Panchanga of Ashwagandha in ASU products based on scientific evidence.
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