Effective On Covid Patients

CoronaVirus Updates

Covid Infection May Up Risk of Psychiatric Disorders: Study

People infected with Covid-19 had a roughly 25 per cent increased risk of developing a psychiatric disorder in the four months following their infection, compared with those who had other types of respiratory tract infections, finds a study. Researchers at Oregon State University in the US found that Covid patients had a 3.8 per cent rate of developing a psychiatric disorder compared with 3.0 per cent for other respiratory tract infections. The 0.8 per cent difference amounts to about a 25 per cent increased relative risk. The team looked specifically at anxiety disorders and mood disorders and found a minor but significant increase in risk for anxiety disorders and no change in risk for mood disorders. The results speak to the need for both patients and health care providers to be more proactive when it comes to addressing mental health concerns following Covid infection, said Lauren Chan, doctoral student in nutrition in OSU's College of Public Health and Human Sciences. "For people that have had Covid, if you're feeling anxiety, if you're seeing some changes in how you're going through life from a psychiatric standpoint, it's totally appropriate for you to seek some help," Chan said. For the study, published in the journal World Psychiatry, researchers included data of 46,610 Covid-19 positive individuals and control patients who were diagnosed with a different respiratory tract infection so they could compare how Covid specifically affected patients' mental health. They looked at the rate of psychiatric diagnoses for two time periods: from 21 to 120 days after patients' Covid diagnosis, and from 120 to 365 days after diagnosis, limited to patients with no previous mental illness. When patients leave a doctor's office, sometimes care stops there, but Chan recommended that providers consider calling in two weeks for a check-in. "I don't want to say that every single person who gets Covid is going to have this type of problem, but if you start to have concern for yourself or a family member, it's not unheard of. You should definitely seek care for yourself or others around you," Chan said. Read More► Dogs Can Detect Covid-19 Faster Than Rapid Antigen Test: Study
CoronaVirus Updates

Dogs Can Detect Covid-19 Faster Than Rapid Antigen Test: Study

London: Dogs are more effective at detecting Covid-19 infections through human sweat samples than the existing rapid antigen tests, according to a study. The study, published in the PLOS ONE, showed that dogs were 97 per cent effective at detecting Covid infection compared to PCR tests - the most accurate Covid test. On the other hand, the nasal antigen tests detected 84 per cent of positive Covid infections. The findings suggest a potentially less invasive and quicker Covid testing alternative. For the study, researchers at the Assistance Publique-Hopitaux de Paris included PCR and sweat samples from 335 people and antigen tests from 234 people recruited in Paris from March 16 and April 9, 2021. The researchers examined five dogs trained to sniff out Covid-19 by examining both positive and negative tests to see if they could tell. They found canines were 100 per cent accurate in detecting positive Covid cases in asymptomatic individuals compared to PCR test results. The canines were slightly less effective at identifying negative coronavirus infections, detecting 90 per cent of negative cases compared to antigen tests that were 97 per cent accurate. "Non-invasive detection of SARS-CoV-2 infection by canine olfaction could be one alternative to nasopharyngeal swabs RT-PCR when it is necessary to obtain a result very quickly according to the same indications as antigenic tests in the context of mass screening," the researchers wrote in the paper. Previous studies have shown dogs to detect malaria, prostate cancer, diabetes, Parkinson's disease and also breast cancer. (Agency) Read More► Diabetes Almost Doubles Risk of Death From Covid: Study
Research

Why Not All Obese Patients

New York: Obesity, often a result of eating too much fat and sugar in combination with low physical activity, is known as a key factor for developing Type 2 diabetes. However, some obese people do not develop the disease that affect millions globally. Turns out their gut bacteria have a role to play. Andrey Morgun and Natalia Shulzhenko of Oregon State University and Giorgio Trinchieri of the National Cancer Institute developed a novel analytical technique, multi-organ network analysis, to explore the mechanisms behind early-stage systemic insulin resistance. The findings, published in the Journal of Experimental Medicine, showed that a particular type of gut microbe leads to white adipose tissue containing macrophage cells, large cells that are part of the immune system, associated with insulin resistance. In the human body, white adipose tissue is the main type of fat. "Our experiments and analysis predict that a high-fat/high-sugar diet primarily acts in white adipose tissue by driving microbiota-related damage to the energy synthesis process, leading to systemic insulin resistance," said Morgun, associate professor of pharmaceutical sciences in the OSU College of Pharmacy. "Treatments that modify a patient's microbiota in ways that target insulin resistance in adipose tissue macrophage cells could be a new therapeutic strategy for Type 2 diabetes," he added. The human gut microbiome features more than 10 trillion microbial cells from about 1,000 different bacterial species. "The so-called 'western diet', high in saturated fats and refined sugars, is one of the primary factors. But gut bacteria have an important role to play in mediating the effects of diet," Shulzhenko said. Experiments in mice, looking at the intestine, liver, muscle and white adipose tissue, the team found "adipose tissue has a predominant role in systemic insulin resistance". Further they "discovered that the Oscillibacter microbe, enriched by a western diet, causes an increase of the insulin-resistant adipose tissue macrophage". The researchers add, however, that Oscillibacter is likely not the only microbial regulator for expression of the key gene they identified, Mmp12, and that the Mmp12 pathway, while clearly instrumental, is probably not the only important pathway, depending on which gut microbes are present. Previously studies have shown that another microbial species "Romboutsia ilealis worsens glucose tolerance by inhibiting insulin levels, which may be relevant to more advanced stages of Type 2 diabetes", Shulzhenko said. (Agency) Read More► Women Should Exercise in The Morning, Men in Evening: Study
CoronaVirus Updates

Diabetes Almost Doubles Risk of Death From Covid: Study

London: People with diabetes were almost twice as likely to die with Covid and almost three times as likely to be critically or severely ill compared to those without diabetes, finds a study. The study conducted by researchers from the University of Aberdeen, UK found patients with diabetes had a significantly higher risk of requiring an intensive care admission and supplementary oxygen or being admitted in a critical condition in comparison to patients without diabetes. However, good control of blood sugar in these patients can significantly reduce this risk. "We found that following a Covid-19 infection, the risk of death for patients with diabetes was significantly increased in comparison to patients without diabetes," said Stavroula Kastora from the varsity. "We also show that good glycaemic control may be a protective factor in view of Covid-19 related deaths," she added, in the paper published in the journal Endocrinology, Diabetes and Metabolism. The team reviewed findings from 158 studies that included more than 270,000 participants from all over the world to determine how Covid affects people living with diabetes. The pooled results showed that people with diabetes were 1.87 times more likely to die with Covid, 1.59 times more likely to be admitted to ICU, 1.44 times more likely to require ventilation, and 2.88 times more likely to be classed as severe or critical, when compared to patients without diabetes.AA Further, the researchers found that patients in China, Korea and the Middle East were at higher risk of death than those from EU countries or the US. They suggest this may be due to differences in healthcare systems and affordability of healthcare. Diabetes is a serious medical condition where blood sugar levels are too high. In 2021, approximately 537 million adults between the 20-79 years were living with diabetes, according to the International Diabetes Federation. The total number of people living with diabetes is projected to rise to 643 million by 2030 and 783 million by 2045. While diabetes increased severity of Covid, a recent study published in the journal Diabetologia, also showed people who have had Covid-19 infection are at increased risk of developing Type 2 diabetes. "In light of the ongoing pandemic, strengthening outpatient diabetes clinics, ensuring consistent follow up of patients with diabetes and optimising their glycaemic control could significantly increase the chances of survival following a Covid infection," Kastora noted. (Agency) Read More► Double-Masking Does Not Improve Protection Against Covid: Study
CoronaVirus Updates

50% Hospitalised Covid Patients Continue to Suffer After 2 Years: Lancet

Two years after infection with Covid-19, half of patients who were admitted to hospital still have at least one symptom, according to the study published in The Lancet Respiratory Medicine. The study followed 1,192 participants in China infected with SARS-CoV-2 during the first phase of the pandemic in 2020. While physical and mental health generally improved over time, the analysis suggests that Covid-19 patients still tend to have poorer health and quality of life than the general population. This is especially the case for participants with long Covid, who typically still have at least one symptom including fatigue, shortness of breath, and sleep difficulties two years after initially falling ill. "Our findings indicate that for a certain proportion of hospitalised Covid-19 survivors, while they may have cleared the initial infection, more than two years is needed to recover fully from it," said lead author Professor Bin Cao, of the China-Japan Friendship Hospital, China. Six months after initially falling ill, 68 per cent of participants reported at least one long Covid symptom. By two years after infection, reports of symptoms had fallen to 55 per cent. Fatigue or muscle weakness were the symptoms most often reported and fell from 52 per cent at six months to 30 per cent at two years. Covid-19 patients were also more likely to report a number of other symptoms including joint pain, palpitations, dizziness, and headaches, pain or discomfort and anxiety or depression than non-Covid-19 participants. Long Covid participants also more often reported problems with their mobility or activity levels than those without long Covid. The authors also acknowledge limitations such as lack of control group of hospital survivors unrelated to Covid-19 infection. The team emphasised the need for follow-up of Covid survivors, particularly those with symptoms of long Covid. "There is a clear need to provide continued support to a significant proportion of people who've had Covid-19, and to understand how vaccines, emerging treatments, and variants affect long-term health outcomes," Cao said. Read More► Asthma in Children Likely to Worsen After Covid Infection: Study
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कोविड रोगियों ने माना स्वस्थ्य

दिल्ली में होम-आइसोलेशन में रहे 92.3 प्रतिशत कोरोना रोगियों ने माना है कि योग ने कोरोना से उबरने में उनकी मदद की है। दिल्ली में कोरोना संक्रमितों के लिए 'दिल्ली की योगशाला' नाम से ऑनलाइन योग क्लासेस शुरू की गई थीं। लगभग 4600 से ज्यादा संक्रमितों को इसका लाभ हुआ है। इस फ्री योग कक्षाओं से संक्रमितों को हुए वास्तविक फायदे की जांच करने के लिए दिल्ली फर्मास्यूटिकल साइंसेज एंड रिसर्च यूनिवर्सिटी द्वारा आईसीएमआर के सीटीआरआई के तहत पंजीकृत एक रिसर्च किया गया। इस रिसर्च में शामिल 92.3 प्रतिशत लोगों ने माना कि संक्रमण के दौरान योग करने से उन्हें कोरोना के सभी लक्षणों में सुधार देखने को मिला और उन्हें सांस फूलने जैसी समस्या नहीं हुई। इस बाबत उपमुख्यमंत्री मनीष सिसोदिया ने कहा कि दिल्ली की योगशाला कार्यक्रम, दिल्ली की जनता को योग के माध्यम से स्वस्थ रखने की एक अनूठी पहल है। उन्होंने कहा कि ये बेहद खुशी की बात है कि जिस उद्देश्य के तहत दिल्ली की योगशाला कार्यक्रम की शुरूआत की गई थी वो पूरा हो रहा है और लोगों को इसका फायदा हो रहा है। उन्होंने कहा कि इस कार्यक्रम के तहत कोरोना के दौरान संक्रमितों को फ्री ऑनलाइन योग कक्षाएं उपलब्ध करवाई गई, जिससे न केवल उन्हें कोरोना से उबरने में मदद मिली बल्कि उनके खांसी, सर्दी, शरीर में दर्द, सांस फूलना आदि जैसे लक्षणों से भी राहत मिली। रिसर्च में शामिल ज्यादातर मरीज 30 से 70 साल के बीच 92.3 प्रतिशत रोगियों ने माना योग करने से कोरोना के लक्षणों में सुधार दिखा। ज्यादातर मरीजों ने माना कि उन्हें संक्रमण के दौरान योग करने से सांस फूलने जैसी समस्या का सामना नहीं करना पड़ा। योग करने से अधिकांश मरीज 5 से 7 दिनों के भीतर कोरोना से उबरे। योग करने वाले केवल 21 संक्रमित ही कोई दवाई ले रहे थे, केवल 26.2 प्रतिशत का ही टीकाकरण हुआ था। ज्यादातर संक्रमितों ने माना योग करने से उन्हें खांसी, सर्दी, शरीर में दर्द, नींद सांस फूलना आदि से जैसे लक्षण से राहत मिली। संक्रमितों ने माना ऑनलाइन योग क्लासेस ने उनके अकेलेपन को खत्म करने के साथ मेंटल हेल्थ को भी बेहतर करने का काम किया। (एजेंसी) यह भी पढ़े► कोविड महामारी अभी खत्म नहीं हुई है: डब्ल्यूएचओ