London, July 17 (IANS) Although the risk of a child being admitted to hospital due to Covid-19 is small, a new UK study has found that around 1 in 20 children hospitalised with Covid developed brain or nerve complications linked to the viral infection.
The research, published in The Lancet Child and Adolescent Health, identifies a wide spectrum of neurological complications in children and suggests they may be more common than in adults admitted with Covid-19.
"The risk of a child being admitted to hospital due to COVID-19 is small, but among those hospitalised, brain and nerve complications occur in almost 4 per cent," said researcher Stephen Ray from the University of Liverpool.
"Our nationwide study confirms that children with the novel post-infection hyper-inflammatory syndrome PIMS-TS can have brain and nerve problems; but we have also identified a wide spectrum of neurological disorders in children due to Covid-19 who didn't have PIMS-TS," Ray added.
While neurological problems have been reported in children with the newly described post-Covid condition paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS), the capacity of Covid-19 to cause a broad range of nervous system complications in children has been under-recognised.
To address this, the researchers developed a real-time UK-wide notification system in partnership with the British Paediatric Neurology Association.
Between April 2020 and January 2021, they identified 52 cases of children less than 18 years old with neurological complications among 1,334 children hospitalised with Covid-19, giving an estimated prevalence of 3.8 per cent.
This compares to an estimated prevalence of 0.9 per cent in adults admitted with Covid-19.
Eight (15 per cent) children presenting with neurological features did not have Covid-19 symptoms although the virus was detected by PCR, underscoring the importance of screening children with acute neurological disorders for the virus.
For the first time, the study identified key differences between those with PIMS-TS versus those with non-PIMS-TS neurological complications.
The 25 children (48 per cent) diagnosed with PIMS-TS displayed multiple neurological features including encephalopathy, stroke, behavioural change, and hallucinations; they were more likely to require intensive care.
Conversely, the non-PIMS-TS 27 (52 per cent) children had a primary neurological disorder such as prolonged seizures, encephalitis (brain inflammation), Guillain-BarrA¿ syndrome and psychosis.
In almost half of these cases, this was a recognised post-infectious neuro-immune disorder, compared to just one child in the PIMS-TS group, suggesting that different immune mechanisms are at work.
Short-term outcomes were good in two-thirds (65 per cent) although a third (33 per cent) had some degree of disability and one child died at the time of follow-up. However, the impacts on the developing brain and longer-term consequences are not yet known.
Jodhpur, June 16 (IANS) Controversial self-styled godman Asaram, who is serving a life sentence in connection with a rape case in Jodhpur jail, was shifted to the AIIMS here on Wednesday after he complained of breathing issues owing to post-Covid complications.On May 7, Asaram was admitted to the ICU of MDM Hospital here after testing positive for Covid-19. Later he was shifted to AIIMS Jodhpur.He started complaining of having breathing problem on Tuesday night and by Wednesday morning, his condition worsened following which he was shifted to the hospital. Initially, he had refused to go the hospital, but got admitted after doctor's advice.After preliminary examination, the doctors told him that he is suffering from post-Covid complications.A few tests have been conducted and a preliminary line of treatment is being given to him, confirmed the medical staff at the hospital.When the self-styled godman was admitted to the hospital last month, he had filed a bail petition in the high court expressing his desire to get treated at an Ayurveda hospital.However, his plea was rejected based on his medical report, which was submitted by the AIIMS medical board on the direction of the high court.Asaram then challenged the high court ruling in the Supreme Court. But the state government then stepped in and opposed granting him bail in the top court, saying that apart from AIIMS, Jodhpur has many renowned institutes of Ayurveda besides having quality medical facilities and hence he should not be granted bail.However, the lawyers of Asaram failed to appear in the Supreme Court on Wednesday, forcing the court to adjourn the hearing to June 18.--IANSarc/arm
Jaipur, June 11 (IANS) Renowned neurologist Ashok Panagariya passed away here on Friday after suffering from post-Covid complications.He was in a hospital for over 25 days as his lungs were damaged even as he recovered from Covid.Panagariya has over 90 research papers in different health journals in his name. He has won UNESCO Award for his medical and social cooperation, and was also conferred the Padma Shri. Chief Minister Ashok Gehlot condoled his death."Condolences to renowned neurologist and Padmashri Dr Ashok Panagariya who served significant positions in the medical stream. Even during COVID pandemic, he played a significant role as a medical practitioner in the state," he said in a tweet.--IANSarc/vd
New York, June 9 (IANS) Covid-19 produced more symptoms and complications than seasonal influenza in children, while death was rare among them, revealed a large new study.Early in the pandemic, opinions around the impact of Covid-19 on children and adolescents ranged from it being no more than the common flu to fear of its potential impact on lesser-developed immune systems.To understand, researchers from IDIAP Jordi Gol in Barcelona compared the real-world observational data of more than 242,000 children and adolescents diagnosed with Covid-19, including nearly 10,000 hospitalised youths, to more than 2,000,000 diagnosed with influenza across five countries (France, Germany, South Korea, Spain, and the US) to provide a clearer picture of Covid's impact.The study, published online in the journal Pediatrics, showed that asthma and obesity were the most common comorbidities. There was also a higher prevalence of rare conditions, including congenital malformations, neurodevelopmental disorders, and heart disease, among those hospitalised with Covid-19.Paediatric patients with Covid-19 also showed higher rates of symptoms such as laboured breathing, loss of smell and gastrointestinal symptoms than those with influenza.The most common 30-day complications for hospitalised youths with Covid-19 were hypoxemia and pneumonia, both of which occurred at a higher rate than hospitalised influenza paediatric patients."This study addressed critical questions that were weighing down on both the healthcare community and the general population -- how was Covid-19 impacting our youngest population," said study lead Talita Duarte-Salles, an epidemiologist at IDIAP Jordi Gol in Barcelona"While some last year claimed that Covid-19 was no different than the flu, the real-world evidence we generated through open science showed something quite different. It was a relief to see that fatality was rare, but clearly both complications and symptoms showed the Covid-19 was no flu in children and adolescents," Duarte-Salles added.--IANSrvt/vd
New York, June 4 (IANS) Covid-19 survivors who have moderate or severe obesity may have a greater risk of experiencing long-term consequences of the disease, compared to the patients who do not have obesity, showed an observational study.Obesity is known to weaken the immune system and create a chronic inflammatory state. These conditions can lead to poor outcomes after an infection with SARS-CoV-2, which is the virus that causes Covid-19, as per the study."To our knowledge, this current study for the first time suggests that patients with moderate to severe obesity are at a greater risk of developing long-term complications of Covid-19 beyond the acute phase," said Ali Aminian, director of Cleveland Clinic's Bariatric & Metabolic Institute.The study, published online in the journal 'Diabetes, Obesity and Metabolism', showed that compared to patients with normal body mass index (BMI), the risk of hospital admission was 28 per cent and 30 per cent higher in patients with moderate and severe obesity, respectively.AIn patients with a BMI of 35 or greater, the need for diagnostic tests to assess cardiac, pulmonary, vascular, renal, gastrointestinal, and mental health problems was significantly higher. compared with normal BMI patients."The observations of this study can possibly be explained by the underlying mechanisms at work in patients who have obesity, such as hyper-inflammation, immune dysfunction, and comorbidities," said Bartolome Burguera, chair of Cleveland Clinic's Endocrinology & Metabolism Institute."Those conditions can lead to poor outcomes in the acute phase of Covid-19 in patients with obesity and could possibly lead to an increased risk of long-term complications of Covid-19 in this patient population," Burguera added.The team included a total of 2,839 patients who did not require ICU admission and survived the acute phase of Covid-19. The normal BMI group was considered as a reference. Obesity is a disease classified as having a BMI of 30 or greater.--IANSrvt/arm
Gurugram, May 31 (IANS) Municipal Corporation of Gurugram (MCG) councillor R.S. Rathee passed away here following Covid-19-related health complications. He was 55.According to officials, Rathee from ward number 34, had tested positive for Covid a few days back and was undergoing treatment at a private hospital.An active activist fighting to save the Aravalli forests, Rathee died late Sunday. His parents passed away on May 12 and 13.MCG Mayor Madhu Azad condoled Rathee's death.On Sunday, 346 people in Gurugram recovered from the virus, while 110 new cases were reported.According to the daily health bulletin, 1,77,297 people have recovered so far in Gurugram.The number of total active case in Gurugram district is 1,727 out of which 1,478 patients are in home isolation.--IANSstr/in