Over the years, there has been a rise in the frequency of heart disease among young adults. This can be attributed to people's changing lifestyles and exposure to too much stress. It is crucial to take note of every item that supports a healthy heart in order to promote one.
Shilajit, a naturally occurring substance found in the Himalayan mountain ranges, has been used for thousands of years in traditional Ayurvedic medicine to treat a variety of illnesses. It is renowned for its exceptional healing properties, which include antioxidant, anti-inflammatory, and anxiolytic.
One of the most significant benefits of Shilajit is its positive impact on heart health. Heart conditions are common and can have serious health repercussions. Taking precautionary measures through the use of Ayurvedic ingredients can be one of the most effective ways to ensure a healthy heart. Here are some of the ways how Shilajit aids in the process:
Improves Heart Health
Studies suggest that Shilajit is one of the core ayurvedic ingredients in improving the health of the heart. It does so by providing strength and energy to the heart to maintain proper blood flow in all parts of the body. Ayurvedic doctors suggest Shilajit as an essential supplement to treat heart diseases as it has health-enduring properties. Since Shilajit contains fulvic acid, iron, and antioxidants like glutathione, the level of glutathione in the body is increased, which creates a line of defense against heart disease.
Lowers Blood Pressure
High blood pressure is a significant risk factor for heart disease. Normal blood pressure is imperative for a healthy life, and Shilajit has been found to lower blood pressure in many cases. The Ayurvedic ingredient can be used as a medium to keep blood pressure under control. This piece of Himalayan rock has worked miracles for mankind, restoring bodily cells that have been impoverished and deprived for a long time so they can operate normally once again. Shilajit blood pressure medication is also beneficial for people with heart and blood pressure issues. Shilajit provides the trace minerals that the body requires for healthy blood pressure regulation and regular bodily functions. Each of these factors makes taking the blood pressure medicine Shilajit particularly useful.
A small study done in 2003 suggested significant improvements in cholesterol levels when around thirty people who were aged 16 to 30 years were given Shilajit. The participants were divided into two groups; the first group took 2 grams of shilajit every day for about 45 days. The cholesterol levels and triglycerides were found to be low in the Shilajit group as compared to those who did not consume Shilajit.
Lowers Blood Fat
Another critical compound in Shilajit is a prominent quantity of humic acid, which can significantly lower blood fats. If the concentration of fats in the body is low, there will be no fat deposits in the blood vessels, which eliminates the blockage of heart vessels. This reduces the risk of hemorrhage and stroke, which are leading causes of death in many patients.
Shilajit is a natural ingredient with many health benefits for the body, especially the heart, as stated in all the aforementioned points. It is a crucial medication for the treatment of heart diseases due to its beneficial effects on arrhythmia, cardiac injury, blood pressure, cholesterol levels, and heart health. (Dr Kriti Soni, Head of R&D, Kapiva).
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अक्सर देखा गया है कि लोग अपने आहार में 'अच्छे' कोलेस्ट्रॉल के स्तर को बढ़ाए रखने का प्रयास करते हैं, मगर नए शोध से पता चला है कि उच्च घनत्व वाले लिपोप्रोटीन (एचडीएल) कोलेस्ट्रॉल हृदय रोग के जोखिम की 'समान रूप से भविष्यवाणी' करने में प्रभावी नहीं हो सकते। नेशनल इंस्टीट्यूट ऑफ हेल्थ (एनआईएच) समर्थित अमेरिकन कॉलेज ऑफ कार्डियोलॉजी की पत्रिका में प्रकाशित एक शोध निष्कर्ष में कहा गया है कि वर्षो पहले एचडीएल कोलेस्ट्रॉल के निम्न स्तर ने गोरे वयस्कों के लिए दिल के दौरे या इससे संबंधित मौतें बढ़ने जोखिम की भविष्यवाणी की गई थी, लेकिन काले वयस्कों के लिए यह सच नहीं था।
इसके अलावा, उच्च एचडीएल कोलेस्ट्रॉल का स्तर किसी भी समूह के लिए कम हृदय रोग जोखिम से जुड़ा नहीं था।
ओरेगॉन हेल्थ एंड साइंस यूनिवर्सिटी, पोर्टलैंड में नाइट कार्डियोवैस्कुलर इंस्टीट्यूट के भीतर चिकित्सा के सहयोगी प्रोफेसर नथाली पामीर ने कहा, "लक्ष्य इस लंबे समय से स्थापित लिंक को समझना था जो एचडीएल को फायदेमंद कोलेस्ट्रॉल के रूप में लेबल करता है, और यदि यह सभी जातियों के लिए सच है।"
पामीर ने कहा, "यह अच्छी तरह से स्वीकार किया गया है कि कम एचडीएल कोलेस्ट्रॉल का स्तर हानिकारक है। हमारे शोध ने उन धारणाओं का परीक्षण किया और पाया कि इसमें गोरे या काले का भेद कोई मायने नहीं रखता।"
इस निष्कर्ष पर पहुंचने के लिए पामीर और उनके सहयोगियों ने स्ट्रोक स्टडी के दौरान भौगोलिक और नस्लीय अंतर को समझने के लिए 23,901 वयस्कों के डेटा की समीक्षा की।
अध्ययन में सबसे पहले पाया गया कि कम एचडीएल कोलेस्ट्रॉल के स्तर ने केवल गोरे वयस्कों के लिए कार्डियोवैस्कुलर बीमारी के जोखिम में वृद्धि की भविष्यवाणी की गई थी।
यह अन्य अध्ययन का निष्कर्ष बताता है कि उच्च एचडीएल कोलेस्ट्रॉल का स्तर हमेशा हृदय संबंधी घटनाओं में कमी नहीं लाता।
पामीर ने कहा, "इस प्रकार के शोध से पता चलता है कि कार्डियोवैस्कुलर बीमारी के लिए जोखिम-भविष्यवाणी एल्गोरिदम पर फिर से विचार करने की जरूरत है। इसका मतलब यह हो सकता है कि भविष्य में एचडीएल कोलेस्ट्रॉल के उच्च स्तर के लिए हमें अपने डॉक्टरों से पीठ नहीं थपथपानी पड़ेगी।"
यह भी पढ़े► प्रदूषित हवा फेफड़ों की बीमारी तक सीमित नहीं
Many young and middle-aged people today are dying of sudden heart attacks. Studies show that cardiovascular diseases (CVD) strike Indians a decade earlier compared to their Western counterparts.
Why is this happening? How can we prevent it? Are we just focused on post-heart attack action? Or should we be focused more on prevention?
Luke Coutinho, Holistic Lifestyle Coach Integrative and Lifestyle Medicine shares an input that could prevent heart attacks at a young age:
Cholesterol is not the culprit, inflammation is: Many people believe that high levels of cholesterol and triglycerides are the sole culprits behind their heart attacks. The main reasons behind most heart attacks are inflammation and oxidative damage in the heart, blood vessels, endothelial lining, arteries, and more. While maintaining healthy cholesterol levels is important, we cannot blame heart attacks on cholesterol levels alone.
What then can you do to keep inflammation in check and your heart strong? Adopt simple lifestyle changes.
Switch From Ordinary Substandard Cooking Oils to Cold-Pressed Oils: Refined oils are highly inflammatory and a threat to your heart. Using refined oils just to save some money isn't a wise idea. Choose the right quality and quantity of oil to boost your heart health. It might cost you a few extra bucks, but remember, your health is not a cost but an investment.
Switch From A Sedentary Lifestyle to An Active One: Even if you don't engage in a full-fledged workout, just stay active. Walking and yoga are the most effective exercises. Choose fun workouts that you enjoy -- dancing, aerobics, Zumba, swimming, whatever it is, but keep that body moving. People who live a sedentary lifestyle are at high risk of heart attacks. Having said that, over-working out with little or no rest or recovery period is equally harmful. So, figure out the adequate level of activity your body needs and stick to it.
Don't Take Matters to Your Heart: Before renting out your heart space and mind space to a person, event or experience, ask yourself if it is worth it. While stress is inevitable, what sets a happy person apart from a stressed person is their capacity to diffuse and navigate stress and see things in a positive light. You can continue attending stress management classes and workshops, and while all of them can help you feel better for some time, the real change happens when you start changing your perspective towards life and how you relate to stress.
Learn to accept and let go. Build your self-worth, create a beautiful inner world, reflect inwards, and allow these teachings to slip into your daily living.
Fix Your Sleep Routine: There is nothing cool about pulling an all-nighter to work or socialize more. Your body only cares about survival. Remember, your sleep is your heart's free drug. The chronic deprivation of it can increase your risk of a heart attack. Your heart is a muscle that needs recovery. Lack of sleep increases your insulin resistance and makes you more prone to type-2 diabetes and a gamut of metabolic conditions. So, adopt a fixed sleeping schedule and sleep deep.
We cannot wait for more misfortunate incidents to realize the importance of lifestyle and start prioritizing it. We must wake up and work towards prevention. Many of us may go through heart disease later in life, no matter how well we exercise or eat clean. So, identify risk factors and work towards tackling them. Even if one of your risk factors is genetic predisposition and there is nothing you can do about it, you can still alter your lifestyle. Our intelligent human body was designed to fix and heal itself. The least we can do is invest in it and help it do its job effectively. Lifestyle can help you bridge this gap.
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Hyderabad, July 27 (IANS) Cells communicate with each other via receptor proteins expressed on the cell membranes, and many drugs target these receptor proteins to alter the cell's functioning and physiology. However, the latest study from Prof Amitabha Chattopadhyay's lab at CSIR-Centre for Cellular and Molecular Biology (CCMB) makes a case for accounting for the lipid environment that surrounds the receptor proteins, while designing drugs, acting on the latter.The lab had earlier found that the serotonin receptors are sensitive to cholesterol surrounding them. In the new study published in Science Advances, they report a sensor region on human serotonin1A receptor that can detect cholesterol. They looked at specific regions called CRAC motifs, believed to interact with cholesterol, in the receptor. The researchers carefully replaced specific amino acids in the CRAC motifs of the serotonin1A receptor, and identified a particular amino acid responsible for cholesterol-sensitive function of the receptor.The researchers collaborated with Dr Jana Selent's group from Pompeu Fabra University Hospital del Mar Medical Research Institute in Spain's Barcelona to visualise the protein-cholesterol interaction via computer-aided molecular dynamics simulations. This helped them predict how the specific amino acid on CRAC motif enables the receptor to sense changes in cholesterol levels by controlling molecular motion in certain regions of the receptor."These findings are important since cholesterol levels change in our cells with age and in many disease conditions. We believe our work will help in developing better drugs that keep in mind not just the receptor as the drug target, but also the lipid environment in which the receptor is present," said Prof Chattopadhyay."Our expertise in structural biology at the CCMB is key towards physical understanding of cells and their functions. This not only adds to the detailed view of living cells but also have immense potential in therapeutics development," CCMB Director, Dr Vinay Nandicoori, said.--IANSms/vd
New York - Researchers have identified a type of "good cholesterol" that protects the liver by blocking inflammatory signals produced by common gut bacteria.
High-density lipoprotein (HDL) is mostly known for mopping up cholesterol in the body and delivering it to the liver for disposal.
But researchers from the Washington University in St Louis, the US, found that a type of "good cholesterol" called HDL3, when produced in the intestine, protects the liver from inflammation and injury. If not blocked, these bacterial signals travel from the intestine to the liver, where they activate immune cells that trigger an inflammatory state, which leads to liver damage.
"Even though HDL has been considered 'good cholesterol,' drugs that increase overall HDL levels have fallen out of favour in recent years because of clinical trials that showed no benefit in cardiovascular disease," said Gwendalyn J. Randolph, Professor of Immunology at the University's School of Medicine.
"But our study suggests that raising levels of this specific type of HDL, and specifically raising it in the intestine, may hold promise for protecting against liver disease, which, like heart disease, also is a major chronic health problem," Randolph added.
The study, published in the journal Science, showed that HDL3 from the intestine protects the liver from inflammation in mice and in human blood samples.
Any sort of intestinal damage can impact how a group of microbes called Gram-negative bacteria can affect the body. Such microbes produce an inflammatory molecule called lipopolysaccharide that can travel to the liver via the portal vein.
The portal vein is the major vessel that supplies blood to the liver, and it carries most nutrients to the liver after food is absorbed in the intestine.
Substances from gut microbes may travel along with nutrients from food to activate immune cells that trigger inflammation. In this way, elements of the gut microbiome may drive liver disease, including fatty liver disease and liver fibrosis, in which the liver develops scar tissue.
"We are hopeful that HDL3 can serve as a target in future therapies for liver disease. We are continuing our research to better understand the details of this unique process," Randolph said. (IANS)
New York,Patients taking statin medications -- commonly used to reduce blood cholesterol levels -- are at a 41 per cent lower risk of in-hospital death from Covid-19, researchers have found.
Statins block liver enzymes responsible for making cholesterol. The US Centers for Disease Control and Prevention estimates that 93 per cent of patients who use a cholesterol-lowering drug use a statin.
The use of statins or an anti-hypertension medication was associated with a 32 per cent lower risk of death among Covid-19 inpatients with a history of cardiovascular disease or hypertension.
This is because statins and anti-hypertension medications stabilise the underlying diseases for which they are prescribed, making patients more likely to recover from Covid-19, according to researchers from the University of California San Diego.
In the study, published in the journal PLOS ONE, the research team analysed anonymised medical records of 10,541 patients admitted for Covid-19 over a nine-month period, January through September 2020, at 104 different hospitals in the US.
"From this data, we performed more advanced analyses as we attempted to control for coexisting medical conditions, socioeconomic status and hospital factors," said lead author Lori Daniels, Professor and director of the Cardiovascular Intensive Care Unit at the varsity's School of Medicine.
"In doing so, we confirmed our prior findings that statins are associated with a reduced risk of death from Covid-19 among patients hospitalised for Covid-19," Daniels added.
The ACE2 receptor -- the regulatory target of statins -- helps control blood pressure. In 2020, it was discovered that SARS-CoV-2 virus primarily uses the same receptor to enter lung cells.
"As with any observational study, we cannot say for certain that the associations we describe between statin use and reduced severity of Covid-19 infection are definitely due to the statins themselves; however, we can now say with very strong evidence that they may play a role in substantially lowering a patient's risk of death from Covid-19," said Daniels.
"We hope that our research findings are an incentive for patients to continue with their medication." (IANS)
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