Washington, June 30 (IANS) Covaxin's Covid-19 jab, developed and manufactured by Hyderabad-based Bharat Biotech, generates antibodies that can effectively neutralise the Alpha (B117) and Delta (B1617) variants of SARS-CoV-2, the virus causing Covid-19, the US National Institutes of Health has said citing results from two studies of blood serum from people who received the shots.Covaxin comprises a disabled form of SARS-CoV-2 that cannot replicate but still stimulates the immune system to make antibodies against the virus.The NIH said an adjuvant, developed by the agency, has also contributed to the success of the highly efficacious Covaxin Covid-19 vaccine, which roughly 25 million people have received to date in India and elsewhere.Adjuvants are substances formulated as part of a vaccine to boost immune responses and enhance a vaccine's effectiveness."Ending a global pandemic requires a global response," said Anthony S. Fauci, director of the National Institute of Allergy and Infectious Diseases (NIAID), part of NIH."I am pleased that a novel vaccine adjuvant developed in the United States with NIAID support is part of an efficacious Covid-19 vaccine available to people in India," he added.The adjuvant used in Covaxin -- Alhydroxiquim-II -- was discovered and tested in the laboratory by the biotech company ViroVax LLC of Lawrence, Kansas with support exclusively from the NIAID Adjuvant Development Programme.The adjuvant comprises a small molecule attached in a unique way to Alhydrogel, a substance frequently called alum that is the most commonly used adjuvant in vaccines for people.Alhydroxiquim-II travels to lymph nodes, where the small molecule detaches from alum and activates two cellular receptors. These receptors, TLR7 and TLR8, play a vital role in the immune response to viruses. Alhydroxiquim-II is the first adjuvant in an authorised vaccine against an infectious disease to activate TLR7 and TLR8.Molecules that activate TLR receptors stimulate the immune system powerfully, but the side effects of Alhydroxiquim-II are mild. This is because, after Covaxin is injected, the adjuvant travels directly to nearby lymph nodes, which contain white blood cells that play an essential role in identifying pathogens and fighting infection.Results from a Phase 2 trial of Covaxin indicate that it is safe and well tolerated, while unpublished interim results from the Phase 3 trial indicate that the vaccine has 78 per cent efficacy against symptomatic disease, 100 per cent efficacy against severe Covid-19, including hospitalisation, and 70 per cent efficacy against asymptomatic infection with SARS-CoV-2.Bharat Biotech signed a licensing agreement with ViroVax to use Alhydroxiquim-II in their candidate vaccines in 2019. This license was expanded during the Covid-19 pandemic to include Covaxin, which has received Emergency Use Authorization in India and more than a dozen other countries.Bharat Biotech developed Covaxin in collaboration with the Indian Council of Medical Research-National Institute of Virology. Bharat Biotech expects to produce an estimated 700 million doses of Covaxin by the end of 2021.--IANSrvt/dpb
Protein is one of the most crucial nutrients required for the healthy functioning of our bodies. The role of protein is commonly misunderstood and is usually associated with muscle gain. Protein has multiple benefits, ranging from metabolism to muscle synthesis. This building block of our body should be an essential part of our diet and should be considered in order to lead a healthier lifestyle.
We all have different protein requirements based on our lifestyles and health factors. For example, a regular, active gym-goer would require more protein per day than your average sedentary man. Pallav Bihani, founder of Boldfit, speaks to IANSlife sharing major symptoms of protein deficiency:
You Can't Seem To Lose The Fat
Have you been working out relentlessly, eating clean and still not seeing a visible difference in your fat loss journey? You need protein. When you don't consume enough protein, your body cannot repair the muscles properly, which eventually leads to the loss of those hard-earned muscles instead of burning fat. Low protein intake can also dip your energy levels marginally, so make sure you are loaded up!
Low protein intake is also linked with unstable moods, irritability and brain fog. Protein is crucial for synthesising a variety of hormones and neurotransmitters responsible for our mood. Such as serotonin, the hormone which makes one feel safe and happy. Missing out on protein can therefore cause fluctuations in one's mood.
Our body requires specific nutrients to be up and running whenever we need to hustle. When you provide inadequate protein, it causes your blood sugar levels to drop, which causes your body to trigger cravings for a quick fix. Consume protein-rich foods to make sure that your blood sugar levels are stable.
Calcium is essential for skeletal integrity, but did you know that 50 per cent of our bones are protein in terms of volume. Along with vitamin D and Calcium, dietary protein is crucial for bone health and longevity. Protein plays a huge role in preserving bone density with ageing.
Skin, Hair and Nail Problems
Your skin, hair and nails are primarily made of protein, and so naturally, a deficiency in protein would reflect on them too. Severe protein deficiency may even cause redness, flaky skin and depigmentation. It may also cause hair thinning, fading, hair loss and brittle nails. Edema, which leads to puffy and swollen skin, is another classic symptom of protein deficiencies.
A safe thumb rule is to consume 1-1.5 grams of protein per kg of bodyweight (i.e.If you weigh 60 kgs, your ideal protein intake goal is between 60 and 90 grams per day). Consume protein from natural sources like meat, eggs, fish, dairy, legumes, soy, and if you cannot meet your goal intake, then invest in protein supplements like whey protein, vegan protein powder and BCAAs.
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New Delhi, June 18 (IANS) The Trained Nurses' Association of India (TNAI) has appealed to the Delhi government to recruit only those people who have completed their nursing training, instead of Class XII pass out, for the specialised jobs, in view of the possible third wave of Covid pandemic.The association said there are many unemployed nurses in Delhi and therefore it is suggested to give appointment only to the nursing personnel with proper salary and working conditions. TNAI in a letter to Chief Minister Arvind Kejriwal on Friday has opposed the Delhi government's recently proposed plan to provide training to youth as Community Nursing to strengthen manpower in hospitals in the wake of possible third wave of the pandemic."You cannot expect an 18-year-old, just a Class 12 pass out selected on 'first come-first served' basis to perform such skilled tasks as administering medicines, injections, vaccination, sample collection and catheterisation after just two weeks training. In fact we may play havoc with the people's health if such perfunctory trained persons are asked to do specialised jobs," said TNAI.The association further said that Delhi-NCR is alone a home to 33 colleges and schools of nursing rating BSc Nursing (600), GNM Nurses (600) and ANM (200) and around 1,500 nurses passing every year. Recently, passed out students from these nursing institutions are being equipped properly to perform their tasks.The letter further read, "We kindly request and direct officers to withdraw this proposal immediately. Also we condemn the use of the term 'Nursing' courses which is not approved by the India Nursing Council or the Sate Nursing Council." Earlier, Kejriwal on Wedenesday announced that the Delhi government will provide training to 5,000 youth, who will be working under the direction of doctors and nurses as health assistants in view of a possible third wave of Covid-19. They will be called Community Nursing assistants.Kejriwal also added that these community nursing assistants will be trained in basic nursing, paramedic, lifesaving, first aid and home care, sample collection, oxygen concentrators and cylinder operations, among other things.--IANSpd/sdr/
Chennai, June 17 (IANS) The Tamil Nadu State Construction Labourers welfare board is all set to fund the vaccination drive of the labourers across the state.The welfare board has a cash surplus of Rs 3,000 crores which is collected as one per cent cess levied from project sites across the state. It is to be noted that around 12.13 lakh workers are registered with the Labour welfare board of Tamil Nadu which is half of the total labour population of the state.It may be noted that several studies have revealed that construction workers are one of the most vulnerable groups to be infected with Covid-19 virus and that the group comprises labourers drawn from Bihar, Chattisgarh, Odisha, West Bengal, Rajasthan, Uttar Pradesh and Madhya Pradesh.A senior officer with the labour department told IANS that the department has already placed an order for 2 lakh doses of Covid-19 vaccines with the Tamil Nadu State Medical Service Corporation.Labour department officials told IANS that a group of 100 to 150 labourers will be vaccinated in one site and this would be carried out across the state.According to the labour department sources, they had earlier conducted a vaccination drive with the Greater Chennai Corporation as the construction workers were considered vulnerable and were given priority vaccination. Sources indicated that around 3,500 construction labourers were vaccinated during the drive-in association with the Greater Chennai Corporation.With the reduced supply of vaccines, the camps which were opened in Chennai and other cities of the state started closing down. Industries and workers associations have made representations with the labour department and suggested that the money with the labour welfare board be utilized for this vaccination drive.The department is now speeding up the vaccination drive among the workers and labourers in Tamil Nadu before the North Indian work force returns to the state. CREDAI officials said that they are into awareness campaign among the labourers to take the jab and how it would prevent them being infected by the virus.--IANSaal/dpb
At the personal level, the fight against the Covid-19 virus begins with strong immunity. As the second wave turns out to be more alarming and devastating than the previous one, many are turning to strengthening their immune system using homegrown plants, 'kadhas', and a nutrient-rich and diverse diet.
The world is waking up again to the importance of a balanced diet, and according to Aseem Sood, Managing Director, Proveda India, it is necessary to follow a diet that includes foods rich in iron, protein and vitamins C, B12 and A.
While patients must strictly follow their doctor's advice, Sood believes that, "to combat this deadly disease is also to opt for the age-old ayurvedic immunity drinks and kitchen ingredients in Indian households that have the necessary nutrients to cure a lot of ailments like cold, flu and fever. Make sure that your immunity is in its prime and working at its full capacity to fight against allergens and pathogens attacking your body."
Here's what he suggests to help you boost your immunity and complete your diet, so your body builds up the strength to put up a fight against foreign pathogens.
Also, Read► 10 easy steps to build a stronger immune system
Giloy and tulsi: Studies have proved that Giloy possesses immune-o-simulator properties. It helps to flush out the toxins from the body. Giloy also contains Antipyretic (fever controlling) properties. Tulsi is known as the ''the queen of herbs''. Tulsi is said to prevent disease, promote general health, well-being and longevity and assist in dealing with the stresses of daily life. Combination of these two superb herbs gives you a healthy and long life. Giloy Tulsi Plus is a traditionally-known herb that boosts immunity level and balances all three 'doshas'.
Panch tulsi with ginger drops: It is one of the best examples of ayurveda's holistic lifestyle approach to health. Considered as a potent adaptogen, Panch tulsi and ginger have a unique combination of pharmacological actions that promote well-being and resilience. This combination increases anti-oxidant molecules such as glutathione and enhancing the activity of antioxidant enzymes such as superoxide dismutase and catalase, which protect cellular organelles and membranes by mopping up damaging free radicals in the body.
Immune drops: Immune drops is a mixture of rama tulsi, kala tulsi, vishnu priya tulsi, sweet lemon tulsi, bisva tulsi, curcumin. It is an instant immunity booster, gives you good health, protects you from diseases and helps you to live a good healthy life.
Sood also suggests taking in dissolvable Vitamin C tablets in water as it is an antioxidant which strengthens body's immune response.
Finally, if one is advised, they can also take in multivitamin capsules. "Modern day food habits don't provide proper nutrition and that's why we need multivitamin supplements to re-vitalize the body and to keep you protected from the damage caused by harmful free radicals.''
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Canberra, June 9 (IANS) Australia's peak medical body has called on the government to implement a tax on sugary beverages to combat obesity, diabetes and poor health.In an address at the National Press Club Wednesday, President of the Australian Medical Association (AMA) Omar Khorshid advocated for a tax that would reduce the consumption of sugary drinks, Xinhua reported."More than 2.4 billion liters of sugary drinks are consumed every year in Australia. That's enough to fill 960 Olympic-sized swimming pools," he said."Diabetes, obesity and poor vascular health are huge contributors to the burden on our health system.""Sugary drinks, and in particular those which have little or no nutritional value, fuel this problem. It is time for action."A study published by the Australian Institute of Health and Welfare in 2019 found that 9.1 per cent of Australian adults consumed sugar-sweetened drinks daily.According to the Australian Bureau of Statistics, an average Australian consumes 60 grams, or 14 teaspoons, of sugar every day.AMA has proposed that the retail price of sugar-sweetened beverages should increase by 20 per cent on average.According to Khorshid, this is in line with a recommendation by the World Health Organisation, and could, over a 25-year period, result in 16,000 fewer cases of type 2 diabetes, 4,400 fewer cases of heart disease and 1,100 fewer cases of stroke."It could save lives, and save millions of dollars in healthcare costs," he said. "It would also generate revenue - we estimate about 814 million Australian dollars (about 630 million US dollars) annually - which we believe could be spent on other preventative health activities."--IANSint/
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