Ayurveda teaches that salt is essential for growth, maintaining water electrolyte balance, and proper digestion, absorption and elimination of wastes. It creates flexibility in the joints, stimulates the appetite and helps digest natural toxins, clearing the subtle channels of the body. It has a calming effect on the nerves and emotions, replenishing and energizing the entire body. Salt balances Vata and can imbalance Pitta and Kapha when used excessively, causing premature wrinkles, thirst, skin problems and weakness.
Throughout time, salt (sodium chloride) has played a vital role in human societies. However, excessive salt consumption could result in serious health problems as it directly impacts the energy levels in one body. Salt is typically made up of the fire and water elements and a small amount regulates moisture level in the body which promotes better absorption of nutrients from food, regulates blood pressure and are vital to the functioning of the brain and nervous system.
Eating too much salt can have a range of effects. In the short term, it may cause bloating, severe thirst, and a temporary rise in blood pressure. In severe cases, it may also lead to hypernatremia, which, if left untreated, can be fatal. In ayurveda,it is established that over indulgence or ati of any ingredient can cause various imbalances in the human body. From a holistic perspective anything overused, misused or used in a high amount leads to an imbalance and causes destruction.
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Similarly, ayurveda teaches that the Sweet taste nourishes and invigorates the mind, relieves hunger and thirst, increases tissues and improves the immune system. Importantly, it is associated with the positive emotions of happiness, contentment, calmness, cheerfulness, love and satisfaction when eaten in appropriate amounts. But again, in moderation. From an Ayurvedic perspective, we need to consider long-term moderation combined with well-timed and precise restraint. Brown sugar, jaggery and natural fruits are used as an alternative to refined sugar. Natural sources of sugar are digested slower and help you feel full for longer. It also helps keep your metabolism stable.
'Ati sevanam' as per Ayurveda might lead to high blood pressure or hypertension involves a disruption of balance in the blood (doshas) one of which is due to excessive salt intake. Whereas high amount of fat intake can cause cholesterol to build up in your arteries (blood vessels), on the other hand too many spices may give acute gastritis, while if consumed in moderation it helps us in combating heart diseases, fight inflammation and keeping the body warm especially in winters. Hence the key is to keep consuming everything in moderation and to avoid 'Atikriya' (overdoing) of everything. Whether it's a food or any activity.
Hence the key is to keep consuming everything in moderation and avoid Atikriya (overdoing) of everything, be it food, lifestyle, indulgence or any activity. As recommended by professionals at Vana, an individual should also practice some of the disciplined lifestyle for a content and mindful living. Some of them are :
Daily Exercising for at least half an hour
Avoid excessive exercises
Avoid suppression of natural urges like that of urine
Avoid daytime sleeping
Avoid excessive stress and anger
Avoid staying awake during night and others
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New York, June 18 (IANS) Administering convalescent plasma from recovered Covid-19 patients can dramatically improve likelihood of survival among blood cancer patients hospitalised with the deadly virus, according to a study.
The study led by researchers from the Washington University in the US indicates a 48 per cent reduced risk of death for Covid patients who had blood cancer and had received convalescent plasma compared to similar patients who did not receive this treatment.
The survival benefit with convalescent plasma was even greater in patients who were admitted to the intensive care unit (60 per cent reduced risk of death) and those who needed mechanical ventilation (68 per cent reduced mortality).
"These results suggest that convalescent plasma may not only help Covid-19 patients with blood cancers whose immune systems are compromised, it may also help patients with other illnesses who have weakened antibody responses to this virus or to the vaccines," said Jeffrey P. Henderson, Associate Professor of medicine and of molecular microbiology at the University's School of Medicine in St. Louis.
"The study also emphasises the value of an antibody therapy such as convalescent plasma as a virus-directed treatment option for hospitalised Covid-19 patients," Henderson added. The findings are published in the journal JAMA Oncology.
The therapy involves transfusing plasma -- the pale yellow liquid in blood that is rich in antibodies -- from people who have recovered from Covid-19 into patients who have leukemia, lymphoma or other blood cancers and are hospitalised with the viral infection. The goal is to accelerate their disease-fighting response. Cancer patients may be at a higher risk of death related to Covid-19 because of their weakened immune systems.
The team studied 143 patients who received convalescent plasma, and 823 who did not. Of the 338 patients admitted to ICUs because of severe Covid-19 symptoms, such as difficulty breathing or cardiac distress, those who received the treatment were more than twice as likely to survive.
In March 2020, the US Food and Drug Administration approved convalescent plasma therapy to Covid patients if requested by their physicians.
Last month the Indian Council of Medical Research dropped the plasma therapy as Covid-19 treatment, citing no significant benefit.
London, June 15 (IANS) A team of scientists has identified how and why some Covid-19 patients can develop life-threatening blood clots.The study, led by researchers at the Royal College of Surgeons in Ireland (RCSI), found the balance between a molecule that causes clotting called the von Willebrand Factor (VWF) and its regulator, ADAMTS13, is severely disrupted in Covid patients who had elevated levels of the VWF protein.The ADAMTS13 gene provides instructions for making an enzyme that is involved in regulating blood clotting, while VWF is a large multimeric glycoprotein in plasma. Deficiency or dysfunction of VWF can lead to either bleeding or thrombosis.The findings could lead to targeted therapies that prevent such clots happening in future, the BBC reported. The study is published in the Journal of Thrombosis and Haemostasis."Our research helps provide insights into the mechanisms that cause severe blood clots in patients with Covid-19, which is critical in developing more effective treatments," said Dr Jamie O'Sullivan, a research lecturer at the RCSI.She said more research needed to be done to determine whether targets aimed at correcting the levels of ADAMTS 13 and VWF can lead to successful interventions."It is important that we continue to develop therapies for patients with Covid-19," O'Sullivan said."Vaccines will continue to be unavailable to many people throughout the world and it is important that we provide effective treatments to them and to those with breakthrough infections," she added.For the study, the team analysed samples from Covid-19 patients in intensive care in the Beaumont Hospital in Dublin.--IANSrvt/vd
New Delhi, June 14 (IANS) Facebook on Monday urged people to donate blood and encourage friends and family to do the same, as part of its campaign for the World Blood Donor Day.World Blood Donor Day is held on June 14 each year.Facebook launched its blood donations feature in 2017 in India. Since then, 60 million people have signed up to receive notifications about donating blood. Globally, over 100 million people have signed up to be blood donors on Facebook since 2017."Facebook's blood donation tool helps connect blood banks with donors to ensure a steady supply of safe blood to those in need especially in these unprecedented times. In India, over 60 million Facebook users have signed up to receive blood donation notifications from blood banks. As part of World Blood Donor Day, we encourage everyone to not only sign up to be a blood donor, but share their experience to inspire others to do the same," said Manish Chopra, Director and Head of Partnerships, Facebook India, in a statement.The Blood Donations feature on the social networking site is a useful tool that connects people to their local blood banks, so they know when there is a shortage and where it is safe to donate.People can sign up to receive notifications about donating blood on Facebook by going to Blood Donations in the 'About' section of their profile. When blood donation centers need donors, they can request donations and send notifications to those nearby who have signed up. People will be able to see requests and opportunities to donate on http://facebook.com/donateblood."We have been using the FB Blood Donation Tool since May 2018. With online mode in place, it's getting easier to find particular group donors through our Facebook posts, which automatically notifies the blood donors. With the reach of the platform and high engagement on the posts, it has become quicker to spread the word in the community," said Dr. Aditi Kumar, Founder, Aarohi Blood Bank, Hyderabad, Telangana.As countries around the world continue to grapple with the ongoing Covid pandemic, blood banks are in urgent need of blood donors.Cricket icon Sachin Tendulkar has also urged fans to donate blood through a video message by speaking about a personal incident and leveraging the power of Facebook communities to reach a wider audience.Covid-19 has intensified India's problem of chronic blood shortage due to lockdown, and fear of infection. In April, last year, the Indian Red Cross Society had raised an alarm that voluntary donation had fallen by almost 100 per cent."Globally, 42 per cent of blood is collected in high-income countries, which are home to just 16 per cent of the world's population. In lower-middle-income countries, the median blood donation rate is 6.8 per 1000 people. In low-income countries, it is five," according to Dr Poonam Khetrapal Singh, WHO Regional Director for South-East Asia."We can all contribute. Throughout the Covid-19 crisis, regular blood donors have continued to give, despite limited mobility and other challenges. Their extraordinary effort has increased health system resilience and must be celebrated for what it is -- a lifesaving gift, and an expression of human solidarity. Throughout the Covid-19 response, but also beyond it, every person's contribution takes us one step closer to achieving Universal Health Coverage, the Flagship Priority and Sustainable Development Goal target that underpins all others," she added.--IANSrvt/sdr/
Mandi, June 14 (IANS) A team of researchers from IIT Mandi has identified the underlying biochemical relationship between the consumption of excessive sugar and the development of afatty liver', medically known as Non-Alcoholic Fatty Liver Disease (NAFLD).
NAFLD is a condition in which excess fat deposits in the liver. The disease starts silently, with no overt symptoms for as much as two decades. If left untreated, the excess fat can irritate the liver cells, resulting in scarring of the liver (cirrhosis), and in advanced cases, can even lead to liver cancer. The treatment of advanced stages of NAFLD is difficult.
One of the causes for NAFLD is the overconsumption of sugar -- both table sugar (sucrose) and other forms of carbohydrates. The consumption of excess sugar and carbohydrates causes the liver to convert them into fat in a process called hepatic De Novo Lipogenesis or DNL, which leads to fat accumulation in the liver.
The molecular mechanisms that increase hepatic DNL due to overconsumption of sugar, which is is key to developing therapeutics for the NAFLD, have not been clear yet, said lead scientist Prosenjit Mondal, Associate Professor, School of Basic Sciences, IIT Mandi.
The team used a complementary experimental approach involving mice models, and identified the unknown link between the carbohydrate-induced activation of a protein complex called NF-KB and increased DNL.
"Our data indicates that the sugar-mediated shuttling of hepatic NF-KB p65 reduces the levels of another protein, sorcin, which in turn activates liver DNL through a cascading biochemical pathway," explained Mondal. The findings are published in the Journal of Biological Chemistry.
The team showed that drugs that can inhibit NF-KB can prevent sugar-induced hepatic fat accumulation. They have also shown that the knockdown of sorcin reduces the lipid-lowering ability of the NF-KB inhibitor.
The finding that NF-KB plays a key role in lipid accumulation in the liver opens up a new avenue of therapeutics for NAFLD. NF-KB also plays a role in other diseases that involve inflammation, such as cancer, Alzheimer's disease, atherosclerosis, IBS, stroke, muscle wasting and infections.
The research comes at a time when India has included NAFLD in the National Programme for Prevention and Control of Cancer, Diabetes, Cardiovascular Diseases and Stroke (NPCDCS).
India is the first country in the world to identify the need for action on NAFLD and with good reason. The prevalence of NAFLD in India is about 9 per cent to 32 per cent of the population, with the state of Kerala alone having a prevalence of 49 per cent and a staggering 60 per cent prevalence among obese school-going children.
The study has conclusively shown that excessive sugar intake leads to a fatty liver. This should offer incentive to the public to reduce sugar intake to stop NAFLD in its early stages, the team said.
Canberra, June 9 (IANS) Australia's peak medical body has called on the government to implement a tax on sugary beverages to combat obesity, diabetes and poor health.In an address at the National Press Club Wednesday, President of the Australian Medical Association (AMA) Omar Khorshid advocated for a tax that would reduce the consumption of sugary drinks, Xinhua reported."More than 2.4 billion liters of sugary drinks are consumed every year in Australia. That's enough to fill 960 Olympic-sized swimming pools," he said."Diabetes, obesity and poor vascular health are huge contributors to the burden on our health system.""Sugary drinks, and in particular those which have little or no nutritional value, fuel this problem. It is time for action."A study published by the Australian Institute of Health and Welfare in 2019 found that 9.1 per cent of Australian adults consumed sugar-sweetened drinks daily.According to the Australian Bureau of Statistics, an average Australian consumes 60 grams, or 14 teaspoons, of sugar every day.AMA has proposed that the retail price of sugar-sweetened beverages should increase by 20 per cent on average.According to Khorshid, this is in line with a recommendation by the World Health Organisation, and could, over a 25-year period, result in 16,000 fewer cases of type 2 diabetes, 4,400 fewer cases of heart disease and 1,100 fewer cases of stroke."It could save lives, and save millions of dollars in healthcare costs," he said. "It would also generate revenue - we estimate about 814 million Australian dollars (about 630 million US dollars) annually - which we believe could be spent on other preventative health activities."--IANSint/