Chennai, June 17 (IANS) Mega star Rajinikanth will leave for the US on Saturday for a routine medical check up.The matinee idol's office in a statement on Thursday said that the actor has completed the shooting of his high budget movie "Annaatthe" in Hyderabad.Rajnikanth, who was all set to join politics had activated the Rajni Fans club "Rajini Makkal Mandram", across the state during 2020 and was to announce his political entry.However, after some health ailments, and on expert medical advise, the he opted out of the race.Rajinikanth had underwent a kidney replacement surgery in the US four years ago.--IANSaal/pgh
If you have felt increased screen time is doing a number on your eyes and potentially contributing to digital eye strain, a survey shows you're not alone. Findings show that 80 per cent of respondents say pandemic-prompted screen time put their eyes in "overdrive".
In fact, two-thirds of respondents report experiencing some degree of eye discomfort every day and nearly a quarter say their eyes feel worse now than they did a year ago. All that is adding up to a new sense of urgency: 90 per cent say it's important to take care of their eyes -- starting now.
The VSP Vision Care survey also found that a quarter say their eyes feel worse now than before the pandemic.
Also, Read► Boost Your Well-Being While in Isolation
Over half of the respondents report looking at a computer most of the day, every day, say the findings, adding that nearly 2 in 3 experience some degree of eye discomfort on a daily basis. Eighty per cent would be willing to schedule routine computer breaks to relieve digital eye strain, while roughly 1 in 5 prioritise paying regular visits to the eye doctor.
In the survey, more than half of respondents defined a "digital detox" as a break from screen time. However, there are other ways to relieve your eyes other than stepping away from screens completely:
Finding relief from digital eye strain: Digital eye strain can occur from prolonged and frequent use of screens, which engages our near vision, and exposes us to the blue light emitted by screens. Symptoms can appear as watery, dry, sore eyes, blurred vision and headaches. Although around 65 per cent report experiencing eye discomfort on a daily basis, half of Americans sometimes miss their annual exam or never go, according to the survey.
Even if you have perfect vision, prolonged screen time -- pandemic-related or not -- can tire out your eyes. During an eye exam, your eye doctor may suggest a computer lens or a blue light-reducing, anti-reflective lens coating that can help reduce your exposure and combat digital eye strain. If you don't wear prescription glasses, non-prescription lenses with a blue light-reducing, anti-reflective coating can be used.
In the 20-20-20 rule, where every 20 minutes, you take 20 seconds to look at something 20 feet away. This will help to reset your focus and help your eyes feel less fatigued due to digital eye strain. Blinking more frequently also helps to relieve discomfort by moistening your eyes.
Keeping an eye out for kids: The survey found that more than half of parents are worried about the effects of their children's increased screen time. Men are more likely than women to be worried about their children's eyes and, when it comes to millennial dads, 6 in 10 are concerned about their children's vision due to increased screen time.
Eye care is health care, and through a comprehensive eye exam, an eye doctor can detect early signs of serious health conditions like diabetes and hypertension.
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Annoyed by pimples? Here’s an ayurvedic guide you need to achieve that flawless skin By Dr. Tabassum Hasan. Do you remember the last time when you were planning to attend a wedding function? From dresses to matching shoes you took care of everything and were ready to dazzle everybody. But guess what? All of a sudden on that very day you got a new pimple on your forehead. Yes, we know how it feels. Those pesky red pimples seem to always appear before any important event in our lives. Almost every one of us suffered this embarrassing situation at some point of our existence, especially in our teenage years. But is there any solution for it? Can we avoid them? What are the causes? Let’s find out answers to all these questions.
Table of contents
• What is Acne?
• Causes and Risk Factor of Acne
• Symptoms of Acne
• When You Need to See Your Doctor
• General Tips For Acne
• What to Eat and Avoid
• Frequently Asked Questions(FAQs)
What is Acne?
In ayurvedic literature, acne has been described as yuvan pidika or tarunya pitika because it primarily affects adolescents or young people. In some texts, it is also called mukh dushika because it spreads mainly on the face of a person and has inflammation and scarring.
Acne is characterized by saruja (mildly painful), filled with meda (pus or oily secretions), shalmali (Salmalia malabarica) thorn-like eruption on the face. These pilosebaceous follicles are distinguished as comedones, papules, pustules, and scars. It mainly affects the cheek, chin, forehead, nose, and upper trunk of the body.
According to global burden of disease (GBD) study, almost 85% of young adults aged between 12-15 years get affected by this dreadful condition. Although it is not a life-threatening condition, but it impacts the social life and emotional well-being of the affected individual.
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Causes and Risk Factor of Acne
According to classical ayurvedic texts, acne is manifested due to vitiated vata dosha and kapha dosha. These doshas further vitiate rasa-raktadi dhatu, primarily rakta dhatu(blood). As result, there is excessive sweda(sweat) production, which obstructs the skin pores. This leads to local swelling and microcomedones formation. Rupture of these micro comedones leads to scarring. Vata dosha and rakta dosha also causes hyperpigmentation.
The factors which lead to all of this are mainly divided into 4 types:
• Time or age factors- young age or adolescents, summers or spring season.
• Dietary pattern- excessive sweet and spicy, heavy and oily food, milk and its products, meat and alcohol.
• Lifestyle factors- Insomnia, holding natural urges, excessive sleep, excessive sunbath.
• Psychological factors- Anger, stress, depression, and behavioral changes.
Other than the above factors, few other factors are also responsible for acne like genetics, hormonal changes, etc. Furthermore, menstrual cycle, anxiety and tension, oil-based makeup, exposure to pollution, skin allergies due to certain medication, hot and humid climate, greasy hair, and squeezing the pimples will make these conditions worse.
Symptoms of Acne
Acne is described under kshudra rogas (minor ailments) in Ayurveda. Kshudra means minimum that means these diseases happen with minimum causative factors, signs and symptoms, and requires minimum medical intervention. Acne also doesn’t have deadly symptoms but it surely affects your self-confidence. Some of these symptoms are stated below-
• Shalmali kantakakara pitika- acne resembles with the thorn of salmalia malabarica as it’s an eruption in a conical shape
• Saruja- These can be mild to moderate painful lumps.
• Ghana- The eruption is hard, thick, or indurated due to vitiated kapha.
• Medogarbha- Due to obstruction of pores or pilosebaceous glands, it is filled with pus.
• Yuna mukhe- This disease usually affects young people or adolescents.
Apart from these symptoms, some associated symptoms are also there like itching, burning, and secretions. Mental health is also affected as it has a huge impact on someone’s looks.
When You Need to See Your Doctor
Generally for acne, people prefer to have OTC (over-the-counter) products. Mild to moderate acne will calm down after the use of these gels or creams in the course of over 4 to 6 weeks. But what if these products stopped working or you have stubborn nodular or cystic acne? Then you definitely need to see your dermatologist. Also if your physical appearance is taking a toll on your mental health, a doctor will help you to combat this situation.
Also, Read► How Stress Impacts Skin: Side Effects & Prevention
General Tips for Acne
Everyone dream to have smooth, silky, and radiant skin. But having acne is a big hurdle to achieve that flawless skin. In this scenario, you can take the help of ayurvedic tips to get rid of those pimples:
• To flush out toxins (ama) in your body, you should take warm water in the morning. Mixing lemon juice in it will also give you a daily dose of vitamin C.
• To balance your body doshas, you can take Triphala. It will remove toxins and reduce your acne. Take 1 teaspoon Triphala powder with warm water.
• Shatavari is also a good ingredient to balance hormones. It will also help in pacifying pitta dosha and treat hormonal acne. You can take one teaspoon of Shatavari powder and boil it in one glass of water. When this will reduce to half, you can consume it.
• Ashwagandha is a popular herb for skin disorders. Its anti-inflammatory, detoxifying properties make it suitable for acne treatment. Take one teaspoon of ashwagandha powder and take it with water or honey.
• Apart from these, blood purifiers told in classical ayurvedic literature like sariva, manjishtha, draksha, and neem are also beneficial for acne treatment. You can include them in your daily routine to purify the blood and balance your doshas. They also have anti-inflammatory and anti-bacterial properties.
• Drinking amla juice daily can help you as amla helps in balancing your doshas. Amla also contains vitamin C which is a potent anti-oxidant. This will reduce harmful free radicals and will keep acne at bay.
• Fennel seeds and coriander seeds concoction is also a good option as it will cool down your body heat. Take one teaspoon of both and boil it in one glass of water. When it will reduce to half, take it after it cools down.
• As clogged pores are the cause of acne, you should wash your face at least twice a day. Use gel-based mild cleansers according to your skin type.
• Avoid touching your face as your fingers usually have bacteria on them. Touching your face can lead to transfer of those bacteria to your face and this can result in infection.
• You should avoid squeezing the pimple. Yes, we know that you have a strong urge to pop that pimple. But always remember that it will lead to more scars.
• Always use a broad spectrum SPF if you are stepping out of your house. Even inside your home, you should at least wear sunscreen of SPF 30.
What to Eat and Avoid
As the saying goes, what you eat appears on your face. This is definitely true in the case of acne. Our skin health says a lot about the way we eat. So if you are someone whose diet is full of junk food and sweetened beverages, then you need to reconsider your food choices. Follow these dietary rules to get rid of your skin ailments and for a healthier complexion-
• Always eat homemade fresh food. Make it light and less spicy.
• Amaranth, barley, oats, rice are healthy grains for you. Include them in your diet.
• Fresh vegetables like bitter gourd, leafy greens, cauliflower, peas, okra, bell peppers are good for your skin and health.
• Soaked almonds and nuts are also a good option as they contain healthy fats that your body needs.
• Eat fruits like apple, oranges, mango, watermelon, dates, figs, pineapple, cherries, grapes, and lime.
• Turkey, salmon, and freshwater fish are the best options if you are a non-vegetarian.
• Always avoid refined grains and sugars like white bread, pasta, noodles, sodas, and artificial sweeteners.
• Heavy and spicy diets create an imbalance between doshas, so try to avoid them.
• Consuming dairy products is also not advised if you are suffering from acne.
• Fast foods like burgers, chowmein, French fries, nuggets, and soda drinks are a big NO if you want to have good and healthy skin.
• Avoid meat (especially red meat) and alcohol consumption as these create havoc on your skin.
Other than that you should keep track if you are allergic to any particular food, foods that may cause bloating or increase inflammation in your body. Just follow these simple rules and you will start noticing a positive difference in your skin soon.
Frequently Asked Questions(FAQs)
Q1. How acne scars can be removed?
Ans. In Ayurveda, there are several local applications for acne scars like haldi, sandalwood, multani mitti. However, in modern medical treatments like microdermabrasion, chemical peeling, micro-needling, fillers, punch excision, and laser resurfacing are prescribed for different types of lesions. Topical treatments like antibiotics (clindamycin and erythromycin), benzoyl peroxides, and vitamin A acid derivatives like tretinoin are also helpful for mild to moderate scars.
Q2. Why acne occurs on the face?
Ans. Acne occurs when your pores get clogged by oil, pus, dead skin, or bacteria. It's like a small red protuberance with pus at its head. This can happen on your shoulders, back, and chest too.
Q3. Which acne cream is best for oily skin?
Ans. Creams with active ingredients like neem, tea tree oil, aloe vera, turmeric are best suitable for acne. In Ayurveda, there are different types of face masks for acne. Some of those are vachaadi lepa, dhanyakaadi lepa, lodhraadi lepa, jayaphalaadi lepa, manjishthaadi lepa and kumkumaadi taila etc. Other than these, you can look for ingredients like bakuchiol, Centella asiatica, honey, colloidal oatmeal, willow bark extract, and resveratrol in your acne products.
Q4. Can acne scars be removed permanently?
Ans. Most of the acne scars get faded over time. As our skin gets renewal after almost 5-6 weeks. That means dead skin cells get replaced by new skin cells. So our scars naturally go away. But in the case of severe scarring, one should get treatment by a dermatologist. They can surely help you to reduce the appearance of your scar.
Q5. Can acne scars be removed naturally?
Ans. Several home remedies like lemon juice, potato juice, turmeric powder, aloe vera, and gram flour are used for ages to remove hyperpigmentation and scars.
• Acharya Sushruta, SushrutaSamhita,AyurvedTatva Sandipika Hindi commentarytranslated by Ambika Datta Shastri, Chaukhamba Sanskrit Sansthan Varanasi, Reprint edition. Nidanasthana, 1995;1(13/38):287.
• Acharya Sushruta, SushrutaSamhita, Acharya YadavjiTrikamji, Choukhambha publication, Varanasi. Edition 2005, Nidanasthana 2005;13/ 39:323.
• Acharya Vaghbhata, Astanga Hrdayam, Dr. Brahamanand Tripathi. Chaukhamba Sanskrit Pratishthan, Delhi, Reprint edition, Sutrasthana, 2009;1(25):19.
• Agnivesh, Charak Samhita, revised by Charak and Dridhabala with Ayurveda Deepika commentary, by Chakrapani Datta, edited by Vd. Yadavaji Trikamaji Acharya, Chaukhamba Surbharati Publications, Varanasi, reprint 2002, Sutrasthana 18/24, S S11/49.
• Lad, Vasant. Textbook of Ayurveda: Fundamental Principles. Albuquerque: The Ayurvedic Press, 2002
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Hyderabad, June 11 (IANS) Hyderabad-based Biophore India Pharmaceuticals announced on Friday that it has applied for DCGI emergency use approval of Aviptadil Inhalation for marketing in India for the treatment of moderate to severe cases of Covid-19.Biophore has successfully developed Aviptadil and is backward integrated with in-house API (Active Pharmaceutical Ingredient).The company will be commencing commercial production immediately after the approval is received from Drugs Controller General of India (DCGI).Aviptadil is a synthetic form of Vasoactive Intestinal Peptide (VIP) that, when administered, results in rapid clinical recovery in patients with severe SARS-COV-2 infection. These observations are based on results of multiple trials of Aviptadil against Covid-19 globally in patients with respiratory failure and the same have been submitted to DCGI for their review, it said."Biophore has developed this highly complex peptide in a very short period of time, primarily due to the extensive focus of the company in prioritizing Covid related products over the last one year. Aviptadil is a very promising treatment option for Covid, especially in severe hospitalized cases where trials have shown a high recovery percentage and we hope to be able to quickly make it available through this approval," said Biophore CEO Jagadeesh Babu Rangisetty.Biophore has been actively involved in developing products against Covid-19 and scaling up manufacturing to meet the requirements. The company was one of the first few manufacturers to have received approval for an anti-viral agent, Favipiravir, in India during the first wave and is also the only Indian manufacturer to be producing multi tonnage volumes of Sulfobutyl Ether beta Cyclodextrin (SBECD), which is a key excipient in the manufacturing of Remdesivir injections.Apart from these, Biophore has invested significantly into the research and development of other anti-Covid products over the last one year"While we are optimistic that the pandemic will end soon, we have to be prepared for the exigencies. We need to keep evaluating and adding newer products against this virus to ensure better preparedness by having more options for the treating physicians and thus avoiding shortages. Our aim is also to make the cost of treatment affordable, especially for hospitalized patients," said Jagadeesh Babu.--IANSms/sdr/
Panaji, June 9 (IANS) In yet another flip flop, Chief Minister Pramod Sawant on Wednesday said that the Goa government had not purchased a single tablet of ivermectin for distribution as part of a prophylaxis treatment protocol, nearly a month after the Health Ministry had announced free distribution of the anti-parasitic drug in Goa for all adults as preventive treatment for Covid-19.Sawant's comment comes two days after the Union Health Ministry dropped ivermectin from its list of drugs to be used while treating Covid patients.Sawant also refuted accusations made by the opposition of an alleged Rs 22.50 crore scam in the purchase of ivermectin for free distribution in Goa, while also adding that there were no differences between him and Health Minister Vishawjit Rane."We had not bought ivermectin for prophylaxis treatment. Not a single (tablet). This figure of Rs 22 crore which is being bandied about is an attempt to create a misunderstanding among people," Sawant told a press conference on Wednesday."We had bought ivermectin, when it was approved by the ICMR (Indian Council for Medical Research) for home isolation kits.A The home isolation kit is recommended by them (ICMR) in other states too. It contained doxycycline, ivermectin, Vitamin C with zinc tablets. We had bought them then," Sawant said.The Chief Minister said that once the ICMR had dropped it from its list of drugs for Covid treatment, the proposal to purchase ivermectin had been dropped.On May 10, the Health Minister had formally announced the free distribution of five ivermectin per adult in Goa, claiming that the drug helps to cut down severity of Covid-19 symptoms, which often leads to fatalities. A day after Rane's announcement a top World Health Organisation scientist had advised against the use of ivermectin for Covid treatment, without requisite tests.The Opposition in Goa has also alleged a scam in the purchase of ivermectin tablets to the tune of Rs 22.50 crore and claimed that the differences between Sawant and Rane had created obstacles in the state's battle against the pandemic, which has so far claimed 2,859 lives.Sawant however said that there were no differences with Rane."There are no differences between me and the Health Minister. There is no misunderstanding. We may have different views on issues, but when it comes to the cabinet, when it comes to the government, when it comes to the state, we are one," Sawant said.--IANSmaya/in
New Delhi, June 8 (IANS) The Chimeric Antigen Receptor T-cell (CAR-T) therapy has emerged as a breakthrough in cancer treatment. Clinical trials conducted globally have shown promising results in end stage patients, especially in patients suffering from Acute Lymphocytic Leukemia -- a type of blood and bone marrow cancer in children.The development of CAR-T cell technology for diseases including acute lymphocytic leukemia, multiple myeloma, glioblastoma, hepatocellular carcinoma and type-2 diabetes.On June 4, TMH, IIT Bombay team and cancer care in India as the first CAR-T cell therapy (a type of gene therapy) was done at the Bone Marrow Transplant unit at ACTREC, Tata Memorial Centre in Mumbai. The CAR-T cells were designed and manufactured at Bioscience and Bioengineering (BSBE) department of IIT Bombay.This work is partly supported by BIRAC-PACE scheme. The TMC-IIT Bombay team are further supported to extend this project for conducting Phase I/II trial of their CAR-T product by DBT/BIRAC, through National Biopharma Mission.Department of Biotechnology has supported First CAR-T cell therapy conducted at ACTREC, Tata Hospital in Mumbai.This is a "first in India" gene therapy in early phase pilot clinical trial and the dedicated efforts and excellent collaboration between IIT Bombay and Tata Memorial Hospital, Mumbai. The Central government's National Biopharma Mission-BIRAC has approved Rs 19.15 crore to the team for conducting a first-in-human phase-1/2 clinical trial of the CAR-T cells.The clinical trials are being done by Gaurav Narula, Professor of Paediatric Oncology and Health Sciences, and his team from TMC, Mumbai, and the novel CAR-T cells that will act as drugs that were manufactured by Prof. Rahul Purwar, Bioscience and Bioengineering (BSBE) department and his team at IIT Bombay. The design, development, and extensive pre-clinical testing was carried out by IIT-B as a collaborative project with Tata Memorial Centre, Mumbai by the two Investigators.IIT-B director Subhasis Chaudhuri said this was a significant feat for the institute as well as the country. "We at IIT-B are delighted that our scientists along with Tata Memorial Hospital have come out with the most sophisticated therapy in cancer treatment. If the trials are successful, it may save millions of lives by making the treatment available in India at an affordable cost. It is a research of IIT-B that is expected to touch the lives of all," said Chaudhuri.National Biopharma Mission is also supporting the development of Lentiviral vector manufacturing facility for packaging plasmids used to transfer the modified T cell inside the body, cGMP facility for T-cell transduction and expansion for CAR T-cell manufacturing to two other organisations.Though this technology has a remarkable therapeutic potential for cancer patients, at present this technology is not available in India. Each patient's CAR-T cell therapy costs 3-4 crore (INR). The challenge therefore is to develop this technology in cost-effective manner and make it available for the patients.The manufacturing complexity is a major reason for the therapy cost. In order to promote and support development of CAR-T cell technology against cancer and other diseases, BIRAC and DBT have taken initiatives and launched specialised calls to invite proposals in the last 2 years.--IANSmiz/pgh