New York, June 27 (IANS) Only 30 per cent of human genes, that are traditional hallmarks of ageing, may be directly involved in the process of ageing, finds a study led by an Indian-American researcher at the US National Institutes of Health (NIH).The study suggests scientists may need to rethink which genes actually control ageing.To understand, the researchers fed fruit flies with antibiotics and monitored the lifetime activity of hundreds of genes that scientists have traditionally thought control ageing.To their surprise, the antibiotics not only extended the lives of the flies but also dramatically changed the activity of many of these genes. Their results suggested that only about 30 per cent of the genes traditionally associated with ageing set an animal's internal clock while the rest reflect the body's response to bacteria."For decades, scientists have been developing a hit list of common ageing genes. These genes are thought to control the aging process throughout the animal kingdom, from worms to mice to humans," said Edward Giniger, from the NIH's National Institute of Neurological Disorders and Stroke (NINDS)."We were shocked to find that only about 30 per cent of these genes may be directly involved in the ageing process. We hope that these results will help medical researchers better understand the forces that underlie several age-related disorders," he added. The findings are published in the journal iScience.For the study, the team raised newborn male flies -- of a type of fruit fly called Drosophila -- on antibiotics to prevent bacteria growth. At first, they thought that the antibiotics would have little or no effect. But, when they looked at the results, they saw something interesting. The antibiotics lengthened the fly's lives by about six days, from 57 days for control flies to 63 for the treated ones."This is a big jump in age for flies. In humans, it would be the equivalent of gaining about 20 years of life," said lead author Arvind Kumar Shukla, post-doctoral researchers at the varsity."We were totally caught off guard and it made us wonder why these flies took so long to die," Shukla added.Shukla and his team looked for clues in the genes of the flies. They used advanced genetic techniques to monitor gene activity in the heads of 10, 30, and 45-day old flies."At first, we had a hard time believing the results. Many of these genes are classical hallmarks of ageing and yet our results suggested that their activity is more a function of the presence of bacteria rather than the ageing process," said Shukla.--IANSrvt/vd
There is a whole gamut of skincare products available right now online and in stores that might give our skin the glow, shine, anti-aging, smoothness that we all crave. But, what happens when we stop using these products? Many of us have an endless list of skin concerns like pigmentation, others about dryness or oiliness, or pimples, or allergies. However, as you grow older, one of the best ways to take care of your skin is to focus on what you eat, rather than what you apply.
Many of us face challenges in deciding what to eat to keep our skin young and healthy, defining a healthy diet, and understanding the role of diet in aging. Currently, the buzzing topic is finding ways to maintain healthy skin and delay skin aging.
According to a study, there is a close association between sugar and some food processing methods (such as grilling, frying, baking, etc) with skin aging, and their mechanisms are related to skin-advanced glycation end products. Skin health is closely linked to nutrition, which is required for all biological processes in the skin, from youth to aging or disease. Nutritional deficiencies and eating habits can both repair and cause damage to the skin.
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There are several simple things we don't follow regularly that can cause skin aging: Not drinking enough water, deficiency of vitamins, proteins, trace elements like zinc, copper, iron, iodine, etc.
Water deficiency in the body can lead to tissue dehydration and functional issues (such as aging and inflammation). Skin is no exception, and the state of moisture in the body is reflected in the appearance of the skin on the lips and limbs. It is advisable to at least drink more than two liters of water every day.
Almonds are a source of 15 nutrients such as vitamin E, magnesium, protein, copper, zinc, iodine, etc. New research suggests that there may be more than one reason to add almonds to your daily skincare routine. The study found that eating almonds daily in place of typical calorie-matched snacks improved measures of both wrinkle severity and skin pigmentation in postmenopausal women. Almonds are known to be a rich source of antioxidant vitamin E and deliver essential fatty acids and polyphenols, which make them a great addition to one's daily diet for improved skin health.
Lack of Vitamin C can also cause skin disorders. They are available in abundance in oranges, lemons, strawberries, and guavas.
All of the body's tissue cells are constantly renewed, and only a sufficient protein intake can keep normal tissue renewal and repair going. The skin is no exception, with a 28-day skin renewal cycle being the norm. Apart from almonds that are rich in protein, you could also consume other protein-rich foods such as yogurt (dahi), lentils, and oats for healthier skin.
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Jerusalem, April 5 (IANS) A team of researchers has identified a set of genes that can tell whether people are heading towards healthy ageing or not.Accumulation of unrepaired DNA damage has been one of the main causes of ageing. These can also lead to neurodegenerative diseases such as Parkinson's and Alzheimer's. The study, published in the journal Ageing, targetted SIRT6 gene -- known to play an instrumental role in DNA repair. The SIRT6 gene was found to have an effect in pathological ageing, but not in normal ageing, said Debra Toiber, from the Ben-Gurion University of the Negev in Israel.The team also determined which genes are better candidates for targeted therapies and whose damage can be reversed by interventions such as calorie restriction. "My research for the last several years has focused on unlocking the secrets of SIRT6, which we discovered, plays a number of prominent roles in ageing," Toiber said. Previous studies show that SIRT6 plays an instrumental role in DNA repair.Its levels were found to decrease in the ageing brain. It serves as a first responder in DNA double strand breaks, immediately going to work but also signalling to other proteins to come help repair the damage. Since there are many changes in ageing and in these pathologies, the researchers compared SIRT6-impaired mice to regular mice, both the same age and compared to older mice. They were able to identify these changes and also find the genes that could predict whether a brain is moving towards healthy ageing or pathological ageing. --IANSrvt/dpb
Dr. Harsh Vardhan, Union Minister for Health & Family Welfare restated commitment of the Government to healthy ageing today on the occasion of International Day for Older Persons. Every year 1st October is celebrated as the International Day of Older Persons, as declared by United Nations, to recognize, enable and expand the contributions of older people in their families, communities and societies at large and to raise awareness towards issues of ageing.
Dr. Harsh Vardhan spoke of the National Programme for the Health Care for the Elderly (NPHCE) which is aimed to deliver comprehensive, affordable and quality geriatric care services at primary and secondary levels; “outpatient services from district hospital to health & wellness centres, minimum 10 bedded geriatric wards at all district hospitals, rehabilitation services down to CHC and HWC level and developing mechanisms for providing home based care to needy elderly.” He elaborated how this would feed into secondary and tertiary institutions through a continuum of care approach. He stated that “19 Regional Geriatric Centres in medical colleges and two National Centres for Ageing are envisioned to render specialized geriatric care through strong cross referrals, developing a strong workforce of geriatricians and geriatric care providers, both medical and paramedical, impart caregiving skills to family members and professionals and carry out need based operational research.”
The Union Health Minister also stated that as 1st October, 2020 is the launch year of Decade of Healthy Ageing (2020-2030), many activities will be undertaken throughout the year, aimed at mainstreaming issues related to elderly and to deliberate upon ways to ensure better and effective delivery of services, making full use of convergence mechanisms. “This initiative is an opportunity to bring together governments, civil society, international agencies, professionals, academia, the media, and the private sector for concerted, catalytic and collaborative action to improve the lives of older people, their families, and the communities in which they live,” he added.
The Minister affirmed that the broad aims of the Decade of Healthy Ageing will include evolving convergence within various national health programs and also promoting inter-sectoral coordination with other line Departments/Ministries. Community based organisations, NGOs and multinational agencies will also be involved for developing an implementation framework for multi-sectoral engagement on healthy aging. “Discussions/workshops/webinars with experts/academic bodies/professionals will be organised to bring out policy and programmatic responses to LASI data, highlighting the best practices for elder care and exploring effective means of promoting and strengthening the participation of older persons in various aspects of social, cultural, economic and civic and political life.”
Highlighting the importance of the Longitudinal Aging Study in India (LASI), he said, “With well-designed and judicious investments, ageing population can help build-up human, social, economic and environmental capital. However, this would call for investing in all the phases of life, fostering enabling societies, and creating flexible but vibrant for building a society for all ages. For this to happen, formulation of policies and programmes of the Government, or any modifications therein to improve their reach and delivery, need to be evidence based. In order to generate comprehensive data on social, economic and health conditions of the elderly, the Government undertook Longitudinal Aging Study of India, the first nationwide study and world’s largest study on older adults which will provide evidence base for national and state level programs and policies for elderly population.” Findings of LASI are being finalised by the Ministry and will be released shortly.
Dr. Harsh Vardhan also spoke on the emergence of COVID-19 as a public health challenge which has caused an upheaval across the country and the world. The UN theme of the International Day of Older Persons 2020 is “Pandemics: Do They Change How We Address Age and Ageing?”. Considering the higher risks faced by elderly during the outbreak of pandemics such as COVID-19, Government has responded to address their concerns by recognising them as vulnerable population category for COVID efforts, issuing advisories, raising awareness of their special needs, encouraging State Governments to develop need-based models for delivery of medications and home-based care to the elderly.
Written by: Sangeeta Singh
SEPTEMBER is known as healthy ageing month !
WHAT DOES IT MEAN?
Worthington is the creator of "September is healthy ageing month, an annual health observance designed to focus national attention on the positive aspects of growing older!
Now it is more than 20 years since it began.
As the topic itself is "healthy ageing month" But do you know an interesting fact of biology- you are only 6 months old! Yes you read right.
Every cell is new in 6 months. Even poets knew that HERACLITUS beautifully wrote "no man ever steps in the same river twice"
As you only know your chronological age. But you, your mind that is your thought process, your consciousness keeps telling new cells about your actual chronological age and that memory is enough for your new cell to feel dull.
Now understand the mind game you are as old as you think, your body and mind is not separated, your each cell have its own memory. So make sure you pore it with all positivity.
Now break the myth that your body and mind are different & think in holistic manner and by thinking that here comes ayurveda for your complete health management which includes every aspects of physical, mental,social and spiritual wellbeing.
Ayurveda is only science which not merely talk about health but also educate you equally how to maintain that health.
As motive of healthy ageing month was to pore the positive aspects of health that "it's never too late to work on your health"
Ahead Ayurveda science gives you proper guidelines to follow accordingly. If we talk about September it's a starting of sarad ritu (likewise each ritu guidelines are mentioned in ayurveda texts)
If we talk about September it's a starting of sarad ritu (likewise each ritu guidelines are mentioned in ayurveda texts)
1. LIFESTYLE IS EVERYTHING
What you eat, drink, think and do each contributes to your health.
Following guidelines of sarad ritu should be adopted!
For eg. Eating light food which is easily digestible like green gram, natural sweet products from plants should be consumed, Gulkand - instead of sugar, sugar candy should be used, sessional vegetables (should be cooked in rock salt-sendha namak), Pure cow ghee should be used externally in your pulses or chapati.
Always eat at hunger strike!
Some don'ts should strictly avoided in this ritu(session) heavy diet including non- veg, excess oil and fried foods, excess exposure to sunlight (as aggravated pitta in your body might get increase by sun exposure during sarad ritu), Day sleeping, excess indulged in sex (once in 3 day is allowed)
2. HEALTHY TIPS
There are some tips which should permanently incorporate in your lifestyles.
Discipline life (flexible lifestyle is the root cause of all disorders), Early to bed early to rise is the first step towards your wellbeing.
Drink warm water after getting up from bed (amount should be according to you as per your body's demands), Take fresh oxygen of early morning, do meditation, pranayam and vyayaam (exercise) as per your wish (for atleast 15 minutes), Fruits should be taken before 12 noon (fruits shouldn't be taken after 12 noon neither after your meal), Same goes with salad (one should eat before meal, neither with meal nor after the meal but it should be taken after 12 noon.
Drink boil water (that water should be taken at normal room temperature, don't force your body to drink hot water). See day sleeping as a crime until it's summer session or you are fully exhausted.
Randoms eating should be avoided (TIP: This could be avoided by differentiating emotional hunger and actual hunger- for eg. One will never wish to eat khichdi in emotional hunger but same one will eat that khichdi in actual hunger)
Eating dinner before 7o'clock or maximum 8o'clock should be adopted. Without rectifying this small mistakes we can't attend health which we unknowingly make but if we are making knowingly than we don't deserve to be healthy.
3. SYMPTOMS SPEAKS
Our body is the greatest system on earth as the sages said "yat pinde tat brahmande" what ever is in universe is present in our body.
So observe your body, little difference wants to tell you alot. So do what your body says to do.
Consult your ayurveda physician as soon as possible on the onset of symptoms (your body don't lie)
Instead suppressing your symptoms, make sure to reverse the pathogenesis by adopting proper guidelines of ayurveda.
4. SELF CONTROL IS GAME CHANGER
People's often demotivate others if someone is following discipline lifestyle by trolling them for not enjoying life.
But the real truth they never get is self control increases your will power. A self control person is much more healthier, happier than others as they have the will power over everything.
For eg. Any preservatives food, junk food or refined products should be avoided by self control and by doing this a drastic improvement in your health will be observed (TIP: excess bakery products, biscuits, namkeen should not consumed on daily basis)
5. BEING HEALTHY IS NOT SHOW OFF
People's think modernization with flexible lifestyle is the way for health but they forget health is not show off.
Which is often justified by phrase " being you" but what is the actual meaning of being you?
Being alcoholic, smoker,drug addict is your "being you" ? Following wrong lifestyle which makes you too obese or too thin is your "being you"? If yes than you are wrong plus you need to change your negative circle who don't point out your mistakes!
Most of the people's don't know but 90% of mental health is because of wrong diet and lifestyle which is adopted in term of modernization as mental health is dependent on physical health and vice-versa which can attend only by correcting current diet and lifestyle by avoiding unnecessary things (which wastes your money,time and health)
"Being you" means courage,strength, not being slave,bold to tell truth, introvert, extrovert etc is the real appraisal things.
6.COSTLY CAN NEVER BE HEALTHY
You have to release a unique way to approach a healthy life.
Many time seeing the way of life people's are approaching towards health is absurd!
We have been taught "heath is wealth" but we hardly see someone who is following.
Instead of that their approach is "wealth is health" but look at yourself, you are sick with all your wealth & if it's so than what is the meaning of wealth if you can't achieve your health?
When a ill person ask me how many day's i have to follow this diet, regimen when can i live my old normal life?
I asked what if your so called normal life with all junk food & habits is not normal?
What if i say, you have to relearn about what is normal?
What if i say, the major population is following abnormal?
What if i say you have a extra blessings of god that you came to know about what is real normal?
THINK ABOUT IT!
we follow abnormal habits, food, lifestyle & then we think it's normal. Which is actually not normal!
Just think how can God make health costly? Health can never be achieved by wealth. But wealth can always be achieved by health.
Attend health, with real normal things don't go with mass population, bless your body by becoming legend, doing extraordinary things in a simple way, in a cheap way.
(TIP: NOT ALL NORMAL THINGS WHICH APPEARS YOU IS NORMAL)
7. EMOTIONAL STABILITY
A destiny without emotional stability can never be achieved, mental peace comes when we are emotionally stable which is attend by having a soulmate, a partner (can be anyone) as world is drowning in chaos of hatred and betrayal but having a partner with whom you feel complete is becoming rarer in this day, so achieving that is equal to success!
8. MENTAL HEALTH
When ever stress,anxiety, depression or such other mental complications comes, give a space for sometime and by giving time apply your all positive energy to improve that situation by making new growth and development again.
Instead of overthinking do some creative work you always want to do that !
For eg. Learning music, doing painting, sketch etc whatever you want!
always remember it's never too late to do anything!
9. FASTING: UNIVERSAL MEDICINE
Fasting is misunderstood by many as per religious point of you!
But fasting have multiple vision which can only understand by broad mindedness
For eg. Fasting from technology, fasting from negative people's, fasting from junk food,fasting from preservatives food ,avoiding non-veg ,avoiding random eatings habit(correcting by taking 2 times of meal)
Following sattivk aahar(which includes fruits) and loving nature.
Fasting one meal food, if though you are keeping full day fast you must know the scientific rules of breaking the fast or how to do the fast( for more details ask your ayurveda physician)
One common mistakes done by people's is eating heavy food durning opening the fast which comes up with many disease ailments so one has to open fast by taking liquid light diet and than gradually go to solid foods.
10. YOUR INNER SOUL IS MIRROR.
What ever we think, what ever our body demands is the reflection of your soul!
Make sure you incorporate positive reflection of your soul by adopting above points in every positive aspects (TIP: making your passion as meditation)
Community Leader - Student Wing - NirogStreet
New York, Aug 24 (IANS) Researchers have found that the expression of a gene associated with ageing is higher in young patients with cancer after chemotherapy treatment and in young cancer survivors who are frail.The study, published in the peer-reviewed journal CANCER, examined the effects of cancer and its treatment on the ageing process.Previous research has shown that a protein called p16INK4a, which slows cell division, is produced at higher levels as a person ages. Using the expression of the gene that codes for p16INK4a as a marker of age, the research team examined immune cells circulating in the blood of young adult survivors of childhood cancers and of children and adolescents newly diagnosed with cancer. "Higher expression of p16INK4a in peripheral blood lymphocytes has been described in older adults following chemotherapy, but prior to this study, not in young adult survivors," said study lead author Andrew Smitherman from the University of North Carolina in the US."This study is important as we try to understand the biological mechanisms underlying the manifestations of early ageing in this population," Smitherman added. The team first analysed cells from 60 survivors and compared them with cells from 29 age-matched individuals without a history of cancer. The findings showed that expression of the gene that codes for p16INK4a was higher in survivors, representing a 25-year age acceleration. Nine survivors were frail, and they had a higher level of expression compared with survivors who were not frail, representing a 35-year age acceleration, the study said.The researchers also found that among the nine children and adolescents part of the study, who had been newly diagnosed of cancer, expression was higher after treatment with chemotherapy than before treatment.Dr. Smitherman noted that elevated p16INK4a expression as a marker of ageing may help identify cancer survivors at the risk of developing frailty and functional disability. "Additionally, expression of p16INK4a may prove useful as a measure to study treatments aimed at mitigating the early ageing effects of cancer treatment," he said.--IANSbu/ptr