लखनऊ | 'डेंटल स्लीप मेडिसिन' पर एक सम्मेलन के अनुसार भारत में करीब 40 लाख लोग, खासकर बुजुर्ग और मोटे लोग ऑब्सट्रक्टिव स्लीप एपनिया (ओएसए) सिंड्रोम से पीड़ित हैं। सोमवार को यहां आयोजित सम्मेलन में विशेषज्ञों ने कहा कि अगर कोई व्यक्ति सांस लेने में तकलीफ के कारण रात में कई बार जागता है और पूरे दिन सिरदर्द और थकान के साथ सुबह शुष्क मुंह का अनुभव करता है, तो यह ओएसए के कारण हो सकता है।
श्वसन चिकित्सा में, ओएसए का आमतौर पर निरंतर पॉजिटिव वायुमार्ग दबाव मशीनों के साथ इलाज किया जाता है, लेकिन दंत चिकित्सा भी आसान प्रबंधन प्रदान करती है।
सरस्वती डेंटल कॉलेज के डीन और सम्मेलन के आयोजक प्रोफेसर अरविंद त्रिपाठी ने कहा, "मोटापा, जीवन शैली का तनाव और दांतों का पूरा गिरना ऊपरी वायुमार्ग में संपीड़न का कारण बन सकता है। यह सांस लेने पर प्रतिकूल प्रभाव डालता है। अगर ऐसी स्थिति लंबे समय तक बनी रहती है और अनुपचारित छोड़ दी जाती है, तो यह शरीर की ऑक्सीजन की आवश्यकता को प्रभावित करती है और हृदय और श्वसन संबंधी समस्याएं पैदा कर सकती है।"
दंत चिकित्सा में, विशेषज्ञों ने कहा, इस स्थिति का इलाज मैंडिबुलर उन्नति उपकरण के साथ किया जा सकता है, एक मौखिक उपकरण जो अस्थायी रूप से जबड़े और जीभ को आगे बढ़ाता है, गले के कसने को कम करता है और वायुमार्ग की जगह को बढ़ाता है।
विश्व स्वास्थ्य संगठन के लखनऊ कार्यालय के डॉ अंकुर ने कहा, "लगभग 80 प्रतिशत रोगियों को नहीं पता कि वे ओएसए से पीड़ित हैं और यह घातक हो सकता है, इसलिए लोगों को इसके बारे में बुनियादी जानकारी होनी चाहिए।"
यह भी पढ़े► कैंसर और हार्ट अटैक से ज्यादा खतरनाक हो जाएगा सेप्सिस: शोध
Nairobi, Aug 18 (IANS) Kenya Red Cross Society said Tuesday that 2.1 million Kenyans are currently facing high acute food insecurity, up from 1.4 million in February due to a worsening drought situation.Asha Mohammed, secretary-general of Kenya Red Cross Society, said that the affected people are in 12 semi-arid and arid counties of the country, the Xinhua news agency reported."The worsening food and nutrition situation is mainly attributed to the poor performance of the October-November-December 2020 and March-April-May rains," Mohammed said, adding that unless urgent multi-sectoral interventions are implemented, the food insecurity situation will get out of hand and affect a total of 20 counties.According to the organisation, the drought-affected counties have had no significant harvest, as most water points such as boreholes, wells and water pans have dried up, increasing distances that people travel looking for water for domestic and livestock use.Mohammed observed that the general lack of water and grazing pasture is fuelling migration and resource-based conflicts while rates of malnutrition in the northeastern part of the country are on the increase.Projections based on weather forecasts indicate that the ongoing drought will persist until early 2022 since climate forecasts for the upcoming short rains beginning in October indicate below-average rains in the water-stressed areas.--IANSint/arm
London, Aug 17 (IANS) Patients with Long Covid syndrome continue to have higher measures of blood clotting, which may help explain their persistent symptoms, such as reduced physical fitness and fatigue, finds a research.
While the dangerous clotting has been observed in patients with severe acute Covid-19, far less is known about Long Covid syndrome, where symptoms can last weeks to months after the initial infection has resolved and is estimated to affect millions of people worldwide.
Researchers from RCSI University of Medicine and Health Sciences in Ireland, examined 50 patients with symptoms of Long Covid syndrome to better understand if abnormal blood clotting is involved.
They discovered that clotting markers were significantly elevated in the blood of patients with Long Covid syndrome compared with healthy controls. These clotting markers were higher in patients who required hospitalisation with their initial Covid-19 infection, but they also found that even those who were able to manage their illness at home still had persistently high clotting markers.
In the study, published in the Journal of Thrombosis and Haemostasis, the team observed that higher clotting was directly related to other symptoms of Long Covid syndrome, such as reduced physical fitness and fatigue. Even though markers of inflammation had all returned to normal levels, this increased clotting potential was still present in the Long Covid patients.
"Because clotting markers were elevated while inflammation markers had returned to normal, our results suggest that the clotting system may be involved in the root cause of Long Covid syndrome," said lead author Dr Helen Fogarty, doctoral student at the Irish Centre for Vascular Biology in the RCSI School of Pharmacy and Biomolecular Sciences.
In a separate study, a team from the University of Cambridge, in the UK, found that small protein molecules called cytokines could have a link to the Long Covid condition, the Daily Mail reported.
Cytokines, which are produced by the body in response to infections, are often found to be lingering in a person's body for months after infection.
They developed a simple new blood test that may determine whether or not Covid-19 survivors will experience long-term symptoms.
Muzaffarpur, July 17 (IANS) With no respite from the sweltering heat and humidity in Bihar, there has been a spurt in Acute Encephalitis Syndrome (AES) cases in children in Muzaffarpur and surrounding areas.
As per the data released by Sri Krishna Medical College and Hospital (SKMCH), Muzaffarpur, 41 children with symptoms of AES were admitted from Muzaffarpur and the adjoining districts, of which 33 children were confirmed to be suffering from AES.
Head of the Department of Paediatrics at SKMCH, GS Sahni, on Saturday said four children are undergoing treatment in the infant ward, in which AES has been confirmed in three children while one other patient is suspected to be suffering from this disease.
Till Friday this year, 41 children have been admitted to SKMCH from Muzaffarpur and surrounding areas reported to be suffering from this disease. As many as nine children have died.
The intensifying heat and humidity makes Muzaffarpur and the surrounding areas susceptible to AES outbreak in children. Every year a large number of children die of this disease.
The worst AES outbreak has been reported in various villages of Minapur, Kanti, Musahari and Paroo blocks of Muzaffarpur district. For the treatment of AES, a special hospital ward has been set up by the health department in Muzaffarpur.
From time to time, awareness campaigns have also been carried out in rural areas by the district administration and the health department but till date they have failed in eradicating this disease. However, a lesser number of patients suffering from this disease have been reported this year.
Toronto, June 21 (IANS) Multisystem inflammatory syndrome is rare but possible in adults who recover from Covid-19, say researchers. The condition has, so far, been detected only in children.
The researchers from University of Calgary in Canada's Alberta stressed the need for clinicians to suspect multisystem inflammatory syndrome in adults when a patient has prolonged fever, with multiorgan involvement, after recovery from SARS-CoV-2 infection, the virus causing Covid-19.
The team described the possibility of the syndrome in adults in a study published in CMAJ (Canadian Medical Association Journal).
The team described a 60-year-old man, who had tested positive for SARS-CoV-2 four weeks before, and visited hospital for a range of symptoms, including prolonged shortness of breath, high fever, swelling and severe fatigue. Tests found an enlarged heart and lung swelling as well as other issues.
"Given the patient's recent history of SARS-CoV-2 infection, fevers without localising symptoms, oral mucosal changes, cervical lymphadenopathy, conjunctivitis and lower extremity changes, we suspected inflammatory post-Covid-19 syndrome," wrote the team including Genevieve Kerkerian and Stephen Vaughan, infectious disease specialists from the varsity's Department of Medicine.
"The presentation was similar to reported cases of an uncommon but severe complication in children and adolescents infected with SARS-CoV-2, called multisystem inflammatory syndrome in children (MIS-C), as well as to Kawasaki-like illness," they added.
Prompt initiation of medication helped the patient to recover.
MIS-C was first described in April 2020 as a hyperinflammatory syndrome with features resembling Kawasaki disease. As of May 3, 2021, 3,742 children in the US had been formally diagnosed with MIS-C, with 35 related deaths.
Much is unknown about multisystem inflammatory syndrome in adults.
In October 2020, the US Centers for Disease Control and Prevention published a review of 27 adult cases that fit the description of a multisystem inflammatory syndrome. The preliminary case of MIS-A, described to date has been in patients younger than 50 years.
"As we continue to learn about MIS-A, however, it is prudent not to assume any age limitation when considering the diagnosis, as our case suggests," the researchers said.
"Unlike for MIS-C, there is currently no requirement to report cases of MIS-A to provincial or state authorities, but this should be encouraged to facilitate research and improve patient outcomes," the authors noted.
Chandigarh, June 20 (IANS) In a first in the world, the Department of Surgical Gastroenterology in the PGI History published a path-breaking study which has established the role of streptokinase in the management of the dreaded disease of severe acute pancreatitis.
Detailing about the study, Rajesh Gupta, Professor and Head, Department of Surgical Gastroenterology, said, "Streptokinase has been used since early 1960's for dissolution of intra-vascular thrombosis in pulmonary thromboembolism, myocardial infarction and deep vein thrombosis.
"The Department of Surgical Gastroenterology in close collaboration with the Department of Medical Gastroenterology started off-label use of streptokinase in 2013.
"The idea to use streptokinase in patients of severe acute pancreatitis was conceptualised after we observed its successful use in chest collections by pulmonologists."
Gupta further elaborated, "We first conducted experimental work in 2013 to look at the effect of streptokinase on pancreatic necrosis removed at the time of surgery and results were heartening.
"This encouraged us to use streptokinase in two patients who were critical and not fit for surgery. We observed that addition of streptokinase in irrigation fluid in abdominal drain led to gradual improvement in their clinical condition and both the patients recovered without need of surgery.
"We published this work in a top journal of pancreatic disease in 2014 namely Pancreatotology."
"After this initial success, we planned the first study in 2015 and subsequently did three more studies including two M.Ch thesis in surgical gastroenterology in collaboration with medical gastroenterology and radiology. We combined data from four studies and published results in one of the top surgical journals namely Surgery," said Gupta.
Attributing the success to the commitment and perseverance of the team comprising of Surinder Rana, Mandeep Kang, Ujjwal Gorsi,A Ritambra Nada and all other senior and junior residents involved in the study, Gupta threw light on the results as he shared, "Results by our study have clearly shown that there was significant decrease in the need of surgery with use of streptokinase and there was no increase in complications with its use which was major apprehensions.A
"Ours is the first large study involving more than 100 patients where streptokinase has been proven efficacious in management of severe pancreatitis with infected necrosis. We have observed that results of streptokinase were better with higher doses."
Gupta added, "We have recently completed another study where we have compared use of streptokinase with another agent i.e. hydrogen peroxide and found encouraging results with streptokinase.
"This study is at present under consideration of another prominent journal. Now, we are planning a bigger study involving various Surgical and Medical Gastroenterology Departments in different parts of the country. This is the first time in the world that streptokinase has been found to be a useful adjunct in management of severe acute pancreatitis".
"It is important to emphasise that the Department of Surgical Gastroenterology and Medical Gastroenterology are top departments in the country in management of severe pancreatitis with a lot of research happening to reduce the complications and deaths in this dreaded disease," said Gupta.